Results 71 to 80 of about 383,452 (267)

Recent advances in multi-objective whale optimization algorithm, its versions and applications

Journal of King Saud University: Computer and Information Sciences
Multi-objective optimization (MO) addresses problems involving multiple conflicting objectives, requiring effective techniques to identify Pareto optimal solutions. Among the numerous MO approaches, the Multi-Objective Whale Optimization Algorithm (MOWOA)
Sharif Naser Makhadmeh, Sofian Kassaymeh, Gaith Rjoub, Bilal Bataineh, Yousef Sanjalawe, Mohammed Azmi Al-Betar   +5 more
doaj   +1 more source

Multi‐objective evolutionary optimization for hardware‐aware neural network pruning

Fundamental Research
Neural network pruning is a popular approach to reducing the computational complexity of deep neural networks. In recent years, as growing evidence shows that conventional network pruning methods employ inappropriate proxy metrics, and as new types of ...
Wenjing Hong, Guiying Li, Shengcai Liu, Peng Yang, Ke Tang   +4 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

A test problem for visual investigation of high-dimensional multi-objective search [PDF]

, 2014
An inherent problem in multiobjective optimization is that the visual observation of solution vectors with four or more objectives is infeasible, which brings major difficulties for algorithmic design, examination, and development.
Yang, S, Li, Miqing; id_orcid, Liu, X, Li, M, Shengxiang Yang, Li, Miqing, Xiaohui Liu, Yang, Shengxiang, Miqing Li, Liu, Xiaohui   +9 more
core   +1 more source

Optimum Nozzle Design for a Viscous Liquid by Using Multi-Objective Search Approaches

IEEE Access, 2020
This work deals with the problem of a nozzle design addressed through a multi-objective optimization strategy where governing equations of fluid dynamics model the phenomena.
Victor Dario Cuervo Pinto, Alejandro Rodriguez-Molina, Leonel German Corona-Ramirez, Miguel Gabriel Villarreal-Cervantes   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source