Results 71 to 80 of about 9,969,039 (243)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Machine learning modeling and multi objective optimization of artificial detrusor

Scientific Reports
To address the problem of obtaining optimal design parameters for existing artificial detrusors using single-objective optimization methods, this research proposed a machine learning-based artificial detrusor modeling and multi-objective optimization ...
Yin Mao, Li Xiao
doaj   +1 more source

Multi-objective optimization of Resin Infusion

Advanced Manufacturing: Polymer & Composites Science, 2019
The present paper addresses the multi-objective optimization of the filling stage of the Resin Infusion manufacturing process. The optimization focuses on the selection of an optimal temperature profile which addresses the tradeoff between filling time ...
G. Struzziero, A. A. Skordos
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Alzheimer's Disease Biomarkers Measured by Capillary Blood Collection Versus Venous Plasma and Cerebrospinal Fluid

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Blood biomarkers are increasingly critical for non‐invasive Alzheimer's Disease (AD) diagnostics and research but typically require on‐site processing. Remote point‐of‐care collection methods could enhance biomarker testing in clinical and research settings.
Sara Ho, Ziling Shen, Alexandria Lewis, Megha Patel, Anny Zheng, Gianna Proscino, Thaovy Ho, Jiangxia Wang, Marilyn Albert, Abhay Moghekar   +9 more
wiley   +1 more source

Different Tools on Multi-Objective Optimization of a Hybrid Artificial Neural Network – Genetic Algorithm for Plasma Chemical Reactor Modelling [PDF]

, 2012
A hybrid ANN-GA was successfully developed to model, to simulate and to optimize simultaneously a catalytic–DBD plasma reactor. The integrated ANN-GA method facilitates powerful modeling and multi-objective optimization for co-generation of synthesis ...
Istadi, Istadi, I. Istadi, Saidina Amin, Nor Aishah, Nor Aishah Saidina Amin   +3 more
core   +2 more sources

MOAVOA: a new multi-objective artificial vultures optimization algorithm

, 2022
This paper presents a multi-objective version of the artificial vultures optimization algorithm (AVOA) for a multi-objective optimization problem called a multi-objective AVOA (MOAVOA).
Gharehchopogh, Farhad Soleimanian, Khodadadi, Nima, Mirjalili, Seyedali   +2 more
core   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Multi-objective optimization of steel nitriding

Engineering Science and Technology, an International Journal, 2016
Steel nitriding is a thermo-chemical process largely employed in the machine components production to solve mainly wear and fatigue damage in materials.
P. Cavaliere, A. Perrone, A. Silvello
doaj   +1 more source

Diffusion Basis Spectrum Imaging of Tissue Microstructure and Early Treatment in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Conventional MRI cannot resolve the coexisting pathological processes within multiple sclerosis tissue. Diffusion Basis Spectrum Imaging decomposes the diffusion signal into fiber, cell, and hindered ratios indexing axonal integrity, cellularity, and extracellular space, respectively.
Apisit Kaewsanit, Aime Luna, Bradley Judge, Nicole Shelley, Karl Friedrichsen, Jayashree Rajamanickam, Zhude Tu, Yong Wang, Tammie L. S. Benzinger, Qing Wang, Matthew R. Brier   +10 more
wiley   +1 more source