Results 231 to 240 of about 3,539,790 (303)

Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen, Yangyi Wang, Tingting Li, Changqing Guo, Zhe Xie, Zhixian Zhang, Xinghua Han, Wei Wang, Jian Wang, Xiaopeng Ma, Yuanzeng Min   +10 more
wiley   +1 more source

Multi-Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis. [PDF]

J Cell Mol Med
Wang Z, Zhao J, Huang X, Chen W, Shen J.
europepmc   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

Genomics and Multi-Omics to Guide Clinical Management in Thyroid Cancer. [PDF]

Int J Mol Sci
Dhieb D, Bastaki K.
europepmc   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

PeachMD: a multi-omics database for peach

Molecular Horticulture
Li, Ang, Sun, Shihang, Wang, Hongmei, Badrunnesa, Akhi, Meng, Junren, Li, Xiongwei, Gao, Yuan, Niu, Liang, Pan, Lei, Duan, Wenyi, Cui, Guochao, Wang, Zhiqiang, Zeng, Wenfang   +12 more
openaire   +2 more sources

Livestock Multi-Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation. [PDF]

Adv Sci (Weinh)
Wen J, Wang Z, Huang J, Li F, Chen N, Ma Y.   +5 more
europepmc   +1 more source

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

Advanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang, Chengfei Jiang, April W. Mao, Qi Sun, Yijun Lu, Jingjing Wei, Jamie L. Inman, Susan E. Celniker, Antoine M. Snijders, David W. Threadgill, Allan Balmain, Bo Hang, Hang Chang, Lei Wang, Jian‐Hua Mao   +14 more
wiley   +1 more source

Insights into the maternal-fetal interface from spatial multi-omics. [PDF]

Front Cell Dev Biol
Wei X, Li Q, Jia H, Qin C, Zou S, Hou Y, Guo Q, Li X, Zhang Y, Wang J, Lin Y.   +10 more
europepmc   +1 more source