Results 41 to 50 of about 6,296,119 (292)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
High-fidelity multi-physics guidelines for model validation and uncertainty quantification
Frontiers in Nuclear EngineeringThe verification, validation, and uncertainty quantification (VVUQ) of high-fidelity, high-resolution multi-physics modeling and simulation in nuclear engineering applications are essential for assessing the predictive credibility of developed models ...
Gregory K. Delipei +3 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Yuanzineng kexue jishuAccurate analysis of reactor core behavior to unlock traditional design margins and enhance the economic efficiency of nuclear power plants has become a key research direction in current reactor design and development.
ZENG Wei1, 2, WANG Jie1, WANG Xiaoyu1, LI Zhigang1, PAN Junjie1, TANG Qifen1
doaj +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Materials & DesignIn hybrid laser-MIG(Metal Inert Gas) welding, multi-physics field prediction in the melting pool is crucial for process optimization and quality control.
Wenbo Zhou +4 more
doaj +1 more source
Theoretical Analysis of Piezoelectric Semiconductor Thick Plates with Periodic Boundary Conditions
Micromachines, 2023 Piezoelectric semiconductors, being materials with both piezoelectric and semiconducting properties, are of particular interest for use in multi-functional devices and naturally result in multi-physics analysis.
Jueyong Zhu +4 more
doaj +1 more source
Multi-Physics Coupling Analysis of Efficient Pumping Unit Linear Motor
, 2017 Taking efficient pumping-unit linear motor as the research object in this paper, SOLIDWORK has been used to establish 3D model and analyze multi-physics of the efficient pumping-unit linear motor, including vibration mode, stress analysis and the ...
Sen Wang +7 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Molecular Oncology, EarlyView.Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi +2 more
wiley +1 more source