Results 11 to 20 of about 47,985 (175)
Learning in multi-agent systems [PDF]
, 2001 In recent years, multi-agent systems (MASs) have received increasing attention in the artificial intelligence community. Research in multi-agent systems involves the investigation of autonomous, rational and flexible behaviour of entities such as ...
Alonso, E. +14 more
core +1 more source
First-Ply Failure Behavior of Laminated Composite Skew Plates of Various Edge Conditions
, 2021 Applications of skew plates in the practical civil engineering are well-established. A look into the papers about the failure of laminated composite structural elements revealed that composite skew plates have not been studied for failure in detail.
Ghosh, A. +2 more
core +1 more source
Literature review: Multi-vessel Coronary Artery Bypass Grafting
, 2022 : Coronary artery bypass grafting (CABG) has developed rapidly in recent years as an important way to treat coronary heart disease. Among them, multi-vessel CABG is considered to improve the long-term patency rate of grafted vessels and improve the long ...
Eric Christian Tchubessi +3 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Weighted Multi Dimensional Logic Programs
, 2004 This book constitutes the strictly refereed post-proceedings of the 4th International Workshop on Computational Logic for Multi-Agent Systems, CLIMA IV, held in Fort Lauderdale, Fl, USA in January 2004. The 11 revised full papers presented together with
Dell Acqua, Pierangelo, +1 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source