Results 121 to 130 of about 11,603,043 (210)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Multi-scale aware turbulence network for underwater object recognition

Frontiers in Marine Science
Underwater imagery is subject to distortion, and the presence of turbulence in the fluid medium poses difficulties in accurately discerning objects.
Meng Zhou, Lei Cai, Jishen Jia, Yuhe Gao
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

A Multi‐Scale Time Adaptive Fusion Network for Transformer Fault Diagnosis

Engineering Reports
Transformer fault diagnosis is crucial for the safe operation of power systems, enabling quick and accurate fault type identification. However, traditional methods struggle with extracting multi‐scale temporal features and high‐order feature ...
XuMing Liu, XiaoKun He, YongLin Li
doaj   +1 more source

Research on Multi-Scale Spatio-Temporal Graph Convolutional Human Behavior Recognition Method Incorporating Multi-Granularity Features

Aiming at the problem that the existing human skeleton behavior recognition methods are insensitive to human local movements and show inaccurate recognition in distinguishing similar behaviors, a multi-scale spatio-temporal graph convolution method ...
Tao Song, Yulin Wang, Yichen Yang, Zheng Hong   +3 more
core   +1 more source

Multi-scale reliability analysis for composite structures

, 2016
Multi-scale reliability analysis for composite ...
X Zhou (5897804), CJ Pearce (7837637), Z Ullah (7837643), L Kaczmarczyk (7837640), PD Gosling (7837634)   +4 more
core   +1 more source

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source