Results 11 to 20 of about 20,830,634 (309)

A framework for multi-scale modelling [PDF]

open access: yesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2014
We review a methodology to design, implement and execute multi-scale and multi-science numerical simulations. We identify important ingredients of multi-scale modelling and give a precise definition of them. Our framework assumes that a multi-scale model can be formulated in terms of a collection of coupled single-scale submodels. With concepts such as
Chopard, B.   +2 more
openaire   +5 more sources

Stress based multi-contact model for discrete-element simulations [PDF]

open access: yes, 2021
The aim of this study is to introduce a stress-based non-binary contact model missing in classical discrete element method (DEM). To tackle this issue, a classical force-displacement contact law is generalized by utilizing the trace of the particle ...
Schilde, C.   +6 more
core   +2 more sources

Illuminating HBV with multi-scale modeling

open access: yesFrontiers in Systems Biology, 2023
Unfortunately for the estimated 250 million sufferers of chronic hepatitis-B viral (HBV) infection worldwide, the liver terrain is typically ignored. An immuno-tolerant environment attractive for pathogens, the essential metabolic roles and structural features of the liver are aligned with distinctive gradients of oxygen and nutrients established along
Shawn A. Means, Md A. Ali, Harvey Ho
openaire   +3 more sources

Data Assimilation in a Multi-Scale Model [PDF]

open access: yesMathematics of Climate and Weather Forecasting, 2017
AbstractData assimilation for multi-scale models is an important contemporary research topic. Especially the role of unresolved scales and model error in data assimilation needs to be systematically addressed. Here we examine these issues using the Ensemble Kalman filter (EnKF) with the two-level Lorenz-96 model as a conceptual prototype model of the ...
Hu, Guannan, Franzke, Christian L. E.
openaire   +2 more sources

Multi-scale Urban integrated assessment model

open access: yes, 2021
A multi-scale integrated assessment model based upon Meadows et al.'s (2005) World 3 modelThis model is described in Purvis, Robinson, & Mao 2022; A multi-scale integrated assessment model to support urban sustainabilityDOI: 10.1007/s11625-021-01080 ...
Ben Purvis (11603107)
core   +1 more source

Multi-scale lung modeling

open access: yesJournal of Applied Physiology, 2011
Multi-scale modeling of biological systems has recently become fashionable due to the growing power of digital computers as well as to the growing realization that integrative systems behavior is as important to life as is the genome. While it is true that the behavior of a living organism must ultimately be traceable to all its components and their ...
Merryn H, Tawhai, Jason H T, Bates
openaire   +3 more sources

Modeling of Bubbly Flow using a Combined Volume of Fluid and Discrete Bubble Model: Investigation on Interphase Forces [PDF]

open access: yesJournal of Applied Fluid Mechanics, 2022
The gas-liquid two-phase flow with interfacial behaviors and bubble-liquid interactions is widely encountered in industrial processes such as that in gas-liquid reactors. The complicated phase structure makes it difficult to be modeled.
H. Yang   +5 more
doaj   +1 more source

Hierarchical Fractional Advection-Dispersion Equation (FADE) to Quantify Anomalous Transport in River Corridor over a Broad Spectrum of Scales: Theory and Applications

open access: yesMathematics, 2021
Fractional calculus-based differential equations were found by previous studies to be promising tools in simulating local-scale anomalous diffusion for pollutants transport in natural geological media (geomedia), but efficient models are still needed for
Yong Zhang   +6 more
doaj   +1 more source

Large-scale brain network model and multi-band electroencephalogram rhythm simulations

open access: yes, 2022
Electroencephalogram (EEG) alpha oscillations play a considerable role in understanding cognitive and physiological aspects of human life, and in diagnosing neurocognitive disorders such as Alzheimer's disease (AD) and dementia.
Wen, Peng, Al-Hossenat, Auhood, Li, Yan
core   +1 more source

Multi-Scale Computational Modeling of Spatial Calcium Handling From Nanodomain to Whole-Heart: Overview and Perspectives

open access: yesFrontiers in Physiology, 2022
Regulation of intracellular calcium is a critical component of cardiac electrophysiology and excitation-contraction coupling. The calcium spark, the fundamental element of the intracellular calcium transient, is initiated in specialized nanodomains which
Michael A. Colman   +6 more
doaj   +1 more source

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