Results 91 to 100 of about 3,103,680 (318)

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Towards a Wearable Inertial Sensor Network [PDF]

open access: yes, 2003
. Wearable inertial sensors have become an inexpensive option to measure the movements and positions of a person. Other techniques that use environmental sensors such as ultrasound trackers or vision-based methods need full line of sight or a local setup,
Nicky Kern   +12 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Data Acquisition, Processing, and Aggregation in a Low-Cost IoT System for Indoor Environmental Quality Monitoring

open access: yesApplied Sciences
The rapid spread of Internet of Things technologies has enabled a continuous monitoring of indoor environmental quality in office environments by integrating monitoring devices equipped with low-cost sensors and cloud platforms for data storage and ...
Alberto Barbaro   +9 more
doaj   +1 more source

Game Design to Measure Reflexes and Attention Based on Biofeedback Multi-Sensor Interaction

open access: yesSensors, 2015
This paper presents a multi-sensor system for implementing biofeedback as a human-computer interaction technique in a game involving driving cars in risky situations. The sensors used are: Eye Tracker, Kinect, pulsometer, respirometer, electromiography (
Inigo de Loyola Ortiz-Vigon Uriarte   +2 more
doaj   +1 more source

Unified clustering and communication protocol for wireless sensor networks [PDF]

open access: yes, 2008
In this paper we present an energy-efficient cross layer protocol for providing application specific reservations in wireless senor networks called the “Unified Clustering and Communication Protocol ” (UCCP). Our modular cross layered framework satisfies
Aslam, Nauman   +2 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Multi-Sensor E-Nose Based on Online Transfer Learning Trend Predictive Neural Network

open access: yesIEEE Access
Electronic Nose (E-Nose) systems, widely applied across diverse fields, have revolutionized quality control, disease diagnostics, and environmental management through their odor detection and analysis capabilities.
Pervin Bulucu   +2 more
doaj   +1 more source

Multi-Sensor Registration in High-Precision CMM Based on a Composite Standard

open access: yesSensors, 2018
Registration is a critical step in multi-sensor dimensional measurement. As the accuracy of registration directly impacts the quality of final results, a reference sphere as a common standard is problematic in high-precision registration.
Yan Zhao   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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