Results 31 to 40 of about 100,134 (293)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Online feature selection for mining big data

open access: yes, 2012
Ministry of Education, Singapore under its Academic Research Funding Tier
HOI, Steven C. H.   +10 more
core   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Mapping and Conceptualizing Big Data and Its Value Across Issues and Domains

open access: yes, 2023
In today’s world, the possibility to collect and analyze unprecedented quantities of data pertaining not only to the operation of private and public sectors, but also to the lives of individuals, bears the potential to employ the data as invaluable ...
Troisi, Orlando   +2 more
core   +1 more source

Unified operation monitoring and security warning platform based on big data in energy group

open access: yesDianxin kexue, 2018
With the increasing of information assets of energy group,in order to effectively cope with information security risks,using the big data and the intersecting confirmation mechanics of multi-source data,a monitoring and security warning platform was ...
Jing WANG   +3 more
doaj   +2 more sources

Agri-BIGDATA: A smart pathway for crop nitrogen inputs

open access: yesArtificial Intelligence in Agriculture, 2020
Big data provide a pathway to lower crop nitrogen inputs from genetic breeding to field production. Moreover, multidisciplinary efforts from plant health sensing, deep machine learning and cloud computing can integrate multi-source data to form ...
Guijun Yang, Yanbo Huang, Chunjiang Zhao
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Cenceptualizing Big Social Data

open access: yes, 2017
The popularity of social media and computer-mediated communication has resulted in high-volume and highly semantic data about digital social interactions.
Kärkkäinen, Hannu   +9 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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