Results 41 to 50 of about 100,134 (293)

Sketch of Big Data Real-Time Analytics Model [PDF]

open access: yes, 2015
Big Data has drawn huge attention from researchers in information sciences, decision makers in governments and enterprises. However, there is a lot of potential and highly useful value hidden in the huge volume of data.
Lu, Joan, Amen, Bakhtiar
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

SocialX: A Modular Platform for Multi-Source Big Data Research in Indonesia

open access: yesCoRR
10 pages, 1 Figure, 4 ...
Muhammad Apriandito Arya Saputra   +4 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Method of improving big data value density based on heterogeneous association

open access: yesDianxin kexue, 2017
The big data resources possessed by telecom operators are usually distributed in many different systems,such as DPI、OIDD、CRM.Moreover,the formulation,interpretation and rules of the big data are not always the same in different systems.Therefore,it is ...
Shaomin WANG, Zheng WANG
doaj   +2 more sources

Enhanced Multi-Level Recommender System Using Turnover-Based Weighting for Predicting Regional Preferences

open access: yesComputers
In the realm of recommender systems, the prediction of diverse customer preferences has emerged as a compelling research challenge, particularly for multi-state business organizations operating across various geographical regions. Collaborative filtering,
Venkatesan Thillainayagam   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Big Data in Massive Parallel Processing

open access: yes, 2018
With the advent of novel wireless technologies and Cloud Computing, large volumes of data are being produced from various heterogeneous devices such as mobile phones, credit cards, and computers.
Woungang, I.,   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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