Results 61 to 70 of about 3,663,409 (288)
Ca2+ transients on the T cell surface trigger rapid integrin activation in a timescale of seconds
Nature CommunicationsOne question in lymphocyte homing is how integrins are rapidly activated to enable immediate arrest of fast rolling lymphocytes upon encountering chemokines at target vascular beds given the slow chemokine-induced integrin inside-out activation.
Yue Li +15 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Biocompatible Magnetopyroelectric Composite Films for Cell Stimulation
Advanced ScienceMagnetoelectric materials, which generate electric fields in response to alternating magnetic stimulation, are increasingly recognized for their applications in neuromodulation, tissue engineering, wireless drug delivery, and cancer treatment. This study
Hao Ye +11 more
doaj +1 more source
Realistic interpretation of a superposition state does not imply a mixture
, 2003 Contrary to previous claims, it is shown that, for an ensemble of either single-particle systems or multi-particle systems, the realistic interpretation of a superposition state that mathematically describes the ensemble does not imply that the ensemble ...
A. Afriat +14 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
IEEE Access, 2019 Motivated by the need to reduce the maintenance cost and improve the system reliability, the issue of selective maintenance has attracted much attention in the industrial and military fields.
Yusheng Wang, Ehsan Elahi, Lei Xu
doaj +1 more source
IET Control Theory & Applications, 2021 The leader‐following consensus problem of a class of non‐strict feedback multi‐agent systems with unknown disturbances, this paper develops a novel adaptive event‐triggered control strategy ground on the consideration of the full state constraints ...
Xi‐Zi Zhang +3 more
doaj +1 more source
, 2017 This paper presents an adaptive harmonic steady-state (AHSS) controller, which addresses the problem of rejecting sinusoids with known frequencies that act on a completely unknown multi-input multi-output linear time-invariant system.
Hoagg, Jesse B., Kamaldar, Mohammadreza
core +1 more source
A Complex Multi-State System with Vacations in the Repair [PDF]
Journal of Mathematics and Statistics, 2019 A complex multi-state system subject to wear failure and given preventive maintenance is considered. Various internal levels of degradation are assumed. The repair facility is composed of a repairperson, who may take one or more vacations during the period considered. A policy is established for the repairperson’s vacation time. Two
openaire +2 more sources