Results 81 to 90 of about 3,663,409 (288)
, 2012 The multi-frontal direct solver is the state-of-the-art algorithm for the direct solution of sparse linear systems. This paper provides computational complexity and memory usage estimates for the application of the multi-frontal direct solver algorithm ...
Calo, Victor M. +3 more
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Cogent Engineering, 2016 This paper presents a mathematical model for a multi-state complex repairable manufacturing system with four types of failures such as common cause, partial, human and catastrophic incorporating waiting time to repair.
Mangey Ram, Monika Manglik
doaj +1 more source
Further developments in modeling digital control systems with MA-prefiltered measurements [PDF]
State variable representations are presented for a continuous-time plant driven by a zero-order-hold with multirate-sampled measurements prefiltered by multi-input/multi-output moving average (MA) processes.
Polites, Michael E.
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Reliability Assessment of Random Uncertain Multi-State Systems
IEEE Access, 2019 The random uncertain multi-state system is defined as a multi-state system consisting of multi-state components whose performance rates and the corresponding state probabilities are presented as uncertain variables. Reliability assessment of random multi-
Linmin Hu, Dequan Yue, Guoxi Zhao
doaj +1 more source
Building on the DEPLOY legacy: code generation and simulation
, 2012 The RODIN, and DEPLOY projects have laid solid foundations for further theoretical, and practical (methodological and tooling) advances with Event-B; we investigated code generation for embedded, multi-tasking systems. This work describes activities from
Butler, Michael +2 more
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