Results 241 to 250 of about 75,387 (288)

Covalent Inhibition of SHMT2 by Gambogic Acid Induces Ferroptosis Through Mitochondrial Collapse in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
In this study, chemoproteomics combined with genetic and functional analyses was integrated to identify SHMT2 as a covalent and functional target of gambogic acid (GA) in triple‐negative breast cancer (TNBC). Further validation demonstrated that GA selectively modifies the Cys241 site of SHMT2, triggering mitochondrial dysfunction, activating the Nrf2 ...
Tong Yang   +15 more
wiley   +1 more source

Dedicated and Reconfigurable Artificial Neurons and Synapses based on Two-Dimensional Materials for Efficient Neuromorphic Application. [PDF]

open access: yesNanomicro Lett
Chen D   +12 more
europepmc   +1 more source

Understanding strain localization in metallic materials: a review of high-resolution digital image correlation and related techniques. [PDF]

open access: yesSci Technol Adv Mater
Briffod F   +5 more
europepmc   +1 more source

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