Results 111 to 120 of about 134,390 (294)

Integrative subspace clustering by common and specific decomposition for applications on cancer subtype identification

BMC Medical Genomics, 2019
Background Recent high throughput technologies have been applied for collecting heterogeneous biomedical omics datasets. Computational analysis of the multi-omics datasets could potentially reveal deep insights for a given disease.
Yin Guo, Huiran Li, Menglan Cai, Limin Li   +3 more
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

DVSAI: Diverse View-Shared Anchors Based Incomplete Multi-View Clustering [PDF]

In numerous real-world applications, it is quite common that sample information is partially available for some views due to machine breakdown or sensor failure, causing the problem of incomplete multi-view clustering (IMVC).
Liu, Zhe, Wang, Miao, Fang, Liming, Wang, Siwei, Wang, Ziming, Zhang, Pei, Zhu, En, Liu, Xinwang, Yu, Shengju   +8 more
core   +1 more source

Multi-view Graph Clustering Algorithm Based on Dual Contrastive Learning and Hard Sample Mining [PDF]

Jisuanji gongcheng
As a key research direction in the field of graph mining, graph clustering aims to discover substructures or node groups with similarities from graph data and classify them into the same cluster.
QIAN Lifeng, LI Jing, ZOU Xuxi, CHEN Yu, GU Yalin, WEI Xunhu
doaj   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

Weighted Multi-View Spectral Clustering Based on Spectral Perturbation [PDF]

, 2018
Considering the diversity of the views, assigning the multiviews with different weights is important to multi-view clustering. Several multi-view clustering algorithms have been proposed to assign different weights to the views.
Zhang, Xianchao, Liu, Xinyue, Zong, Linlin, Yu, Hong   +3 more
core   +1 more source

netMUG: a novel network-guided multi-view clustering workflow for dissecting genetic and facial heterogeneity. [PDF]

Front Genet, 2023
Li Z, Melograna F, Hoskens H, Duroux D, Marazita ML, Walsh S, Weinberg SM, Shriver MD, Müller-Myhsok B, Claes P, Van Steen K.   +10 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Double Self-weighted Multi-view Clustering via Adaptive View Fusion [PDF]

, 2022
Multi-view clustering has been applied in many real-world applications where original data often contain noises. Some graph-based multi-view clustering methods have been proposed to try to reduce the negative influence of noises.
Fang, Xiang, Hu, Yuchong
core   +1 more source