Results 31 to 40 of about 9,250,525 (285)

Sistem Pendukung Keputusan Pemilihan Jasa Travel Menggunakan Metode Multi Attribute Utility Theory

open access: yesJurnal Ilmiah Computer Science
Decision Support System (DSS) is an information system designed to assist decision makers in the process of data analysis and evaluation of alternatives to achieve certain goals.
Donaya Pasha
doaj   +1 more source

Automated Probabilistic System Architecture Analysis in the Multi-Attribute Prediction Language (MAPL): Iteratively Developed using Multiple Case Studies

open access: yesComplex Systems Informatics and Modeling Quarterly, 2017
The Multi-Attribute Prediction Language (MAPL), an analysis metamodel for non-functional qualities of system architectures, is introduced. MAPL features automate analysis in five non-functional areas: service cost, service availability, data accuracy ...
Robert Lagerström   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Implementation of Multi-Attribute Utility Theory (MAUT) method for selecting diplomats

open access: yesIOP Conference Series: Materials Science and Engineering, 2021
Abstract Diplomatic relations between countries increasingly show how important the meaning of relations between these countries. Representatives are needed in order to establish cooperative relationships in several fields such as culture, politics, and education.
I Taufik   +4 more
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A comparison of five multi attribute utility instruments [PDF]

open access: yes, 2003
This paper presents the results of the validation study carried out to evaluate the Assessment of Quality of Life (AQoL) Instrument for the measurement of health related quality of life and utility.
Jeff Richardson   +5 more
core  

Digital Twin-Enabled Decision Support in Mission Engineering and Route Planning

open access: yesSystems, 2021
This article presents a Model-Based Systems Engineering (MBSE) methodology for the development of a Digital Twin (DT) for an Unmanned Aerial System (UAS) with the ability to demonstrate route selection capability with a Mission Engineering (ME) focus. It
Eugene Boon Kien Lee   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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