Results 61 to 70 of about 260,507 (305)

Deforestation Risk Zoning Using Analytical Hierarchy Process

open access: yesجغرافیا و پایداری محیط, 2020
This study aimed to identify the most influential factors in deforestation using multi-criteria decision-making method in a part of northern Zagros forests in Iran with a total area of 9177 hectares.
Hiva Mahmoudi   +2 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Penggunaan Algoritma Multi Criteria Decision Making dengan Metode Topsis dalam Penempatan Karyawan

open access: yesJurnal EECCIS (Electrics, Electronics, Communications, Controls, Informatics, Systems), 2015
The employees are a major asset in the company so that the company can operate properly. In employees pacement, often a mismatch between the positions of the competence of employees.
Agung N. Pramudhita   +2 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Water allocation for agricultural users based on multi criteria analysis and use of decision-making tools

open access: yes, 2019
Recent research has signaled promising options to create a unique framework to integrate multi-criteria optimization tools with river basin simulation-optimization models.
Zoranovic, Tihomir   +4 more
core   +1 more source

A multi-criteria decision making approach for food engineering

open access: yes, 2011
The objective of this study was to propose a decision making approach and tools (software packages) to solve the multi-criteria decision making problems arising in the food engineering.
Abakarov, Alik
core  

Sustainable Supply Chain Management and Multi-Criteria Decision-Making Methods: A Systematic Review

open access: yes, 2021
Multi-criteria decision-making (MCDM) methods are smart tools to deal with numerous criteria in decision-making. These methods have been widely applied in the area of sustainable supply chain management (SSCM) because of their computational capabilities.
Ananna Paul   +11 more
core   +1 more source

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