Results 61 to 70 of about 380,664 (276)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Predicting 28-day compressive strength of fibre-reinforced self-compacting concrete (FR-SCC) using MEP and GEP

open access: yesScientific Reports
The utilization of Self-compacting Concrete (SCC) has escalated worldwide due to its superior properties in comparison to normal concrete such as compaction without vibration, increased flowability and segregation resistance.
Waleed Bin Inqiad   +3 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Dataset used to develop soft computing models that predict the stiffness modulus of bituminous mixtures

open access: yesData in Brief
This data article presents information on the measurement of Indirect Tensile Stiffness Modulus of laboratory and field asphalt mixtures. The asphalt mixes are composed of three distinct binders that were categorised by their penetration grade (40/55-TLA,
Lee P. Leon   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

MINLP model for operation optimization of multi-source single-sink liquid light hydrocarbon pipeline network system

open access: yesYou-qi chuyun, 2020
At present, batch mixed transportation mode is mainly adopted in the multi-source single-sink liquid light hydrocarbon pipeline network system of China's oil and gas fields.
Rui QIU   +5 more
doaj   +1 more source

Merlin: A Language for Provisioning Network Resources [PDF]

open access: yes, 2014
This paper presents Merlin, a new framework for managing resources in software-defined networks. With Merlin, administrators express high-level policies using programs in a declarative language.
Emin Gün   +7 more
core   +5 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A Probabilistic Extension of Action Language BC+

open access: yes, 2018
We present a probabilistic extension of action language BC+. Just like BC+ is defined as a high-level notation of answer set programs for describing transition systems, the proposed language, which we call pBC+, is defined as a high-level notation of ...
Lee, Joohyung, Wang, Yi
core   +1 more source

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