Results 91 to 100 of about 52,301 (321)
Interacting cells driving the evolution of multicellular life cycles
, 2019 Author summary Multicellular organisms are ubiquitous. But how did the first multicellular organisms arise? It is typically argued that this occurred due to benefits coming from interactions between cells. One example of such interactions is the division
Gao, Y., Pichugin, Y., Traulsen, A.
core +2 more sources
Pluripotency and the origin of animal multicellularity
Nature, 2019 A widely held—but rarely tested—hypothesis for the origin of animals is that they evolved from a unicellular ancestor, with an apical cilium surrounded by a microvillar collar, that structurally resembled modern sponge choanocytes and choanoflagellates1 ...
Shunsuke Sogabe +8 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Frontiers in Microbiology, 2015 Multicellularity has emerged and continues to emerge in a variety of lineages and under diverse environmental conditions. In order to attain individuality and integration, multicellular organisms must exhibit spatial cell differentiation, which in turn ...
Emilio eMora Van Cauwelaert +8 more
doaj +1 more source
Cellular organization in lab-evolved and extant multicellular species obeys a maximum entropy law
eLife, 2022 The prevalence of multicellular organisms is due in part to their ability to form complex structures. How cells pack in these structures is a fundamental biophysical issue, underlying their functional properties.
Thomas C Day +11 more
doaj +1 more source
Evolution of Helping and Harming in Viscous Populations When Group Size Varies [PDF]
, 2013 Funding: Balliol College and the Royal Society.Recent years have seen huge interest in understanding how demographic factors mediate the evolution of social behavior in viscous populations.
Gardner, Andy, Rodrigues, Antonio M. M.
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FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Understanding Microbial Divisions of Labor [PDF]
, 2016 Divisions of labor are ubiquitous in nature and can be found at nearly every level of biological organization, from the individuals of a shared society to the cells of a single multicellular organism.
Daniel E. Rozen +2 more
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A mechanistic explanation of the transition to simple multicellularity in fungi
Nature Communications, 2020 Development of multicellularity was one of the major transitions in evolution and occurred independently multiple times in algae, plants, animals, and fungi.
Luke Heaton, N. Jones, M. Fricker
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Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source