Exploring the roles of conserved context-dependent cis-regulatory elements (cdCREs) in multicellularity, human health and disease. [PDF]
McEwan A +5 more
europepmc +1 more source
Insights into the Evolution of Multicellularity from the Sea Lettuce Genome
O. Clerck +35 more
semanticscholar +1 more source
3D Hydrogel Cell Cultures and Their Biomedical Applications
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai +7 more
wiley +1 more source
Continuous emergence of phototaxis in Dictyostelium discoideum. [PDF]
Genettais D +4 more
europepmc +1 more source
Mucin Glycoprotein Nanoparticles Enable a Selective Antisense Therapy for Oncogenic MicroRNAs
Mucin glycoproteins are turned into nanoparticles by employing synthetic DNA strands, which have a dual function: they stabilize the nanoparticles and act as binding sites for intracellular miRNA‐21. Thus, upon internalization into tumor cells, these mucin nanoparticles can deplete miRNA‐21 from the cytosol, which induces apoptosis in vitro and in vivo.
Ceren Kimna +9 more
wiley +1 more source
Resolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges. [PDF]
Espinoza Miranda SS +11 more
europepmc +1 more source
Nanoclay‐Engineered Scaffolds for the Controlled Delivery of Biomolecules in Regenerative Medicine
ABSTRACT Regenerative medicine combines biomaterials, cells, scaffolds, and bioactive agents via modern technologies to aid in the reconstruction and repair of damaged tissues. Among these, nanoclay scaffolds have demonstrated unique advantages in facilitating the delivery of therapeutic agents.
Mehri Shadi +2 more
wiley +1 more source
A reassessment of the "hard-steps" model for the evolution of intelligent life. [PDF]
Mills DB +3 more
europepmc +1 more source
Abstract A recent debate has emerged between Caspar et al. (2024) and Herculano‐Houzel (2023) on inferring extinct dinosaur cognition by estimating brain neuron counts. While thought‐provoking, the discussion largely overlooks the function of cognition, as well as partly neglects the difficulties involved in estimating neuron numbers, which according ...
Thomas Rejsenhus Jensen +7 more
wiley +1 more source
The Proteome of <i>Dictyostelium discoideum</i> Across Its Entire Life Cycle Reveals Sharp Transitions Between Developmental Stages. [PDF]
Banu S +5 more
europepmc +1 more source

