Results 51 to 60 of about 52,301 (321)

Phylostratigraphic tracking of cancer genes suggests a link to the emergence of multicellularity in metazoa

BMC Biology, 2010
Background Phylostratigraphy is a method used to correlate the evolutionary origin of founder genes (that is, functional founder protein domains) of gene families with particular macroevolutionary transitions.
Domazet-Lošo Tomislav, Tautz Diethard
doaj   +1 more source

In silico transitions to multicellularity

, 2014
The emergence of multicellularity and developmental programs are among the major problems of evolutionary biology. Traditionally, research in this area has been based on the combination of data analysis and experimental work on one hand and theoretical ...
Duran-Nebreda, Salva, Solé, Ricard V.
core   +1 more source

Evolution of an ancient protein function involved in organized multicellularity in animals. [PDF]

, 2016
To form and maintain organized tissues, multicellular organisms orient their mitotic spindles relative to neighboring cells. A molecular complex scaffolded by the GK protein-interaction domain (GKPID) mediates spindle orientation in diverse animal taxa ...
Anderson, Douglas P, Campodonico-Burnett, William, Hanson-Smith, Victor, King, Nicole, Prehoda, Kenneth E, Thornton, Joseph W, Volkman, Brian F, Whitney, Dustin S, Woznica, Arielle   +8 more
core   +2 more sources

Cryogenian Origins of Multicellularity in Archaeplastida

Genome Biology and Evolution
Earth was impacted by global glaciations during the Cryogenian (720 to 635 million years ago; Ma), events invoked to explain both the origins of multicellularity in Archaeplastida and radiation of the first land plants. However, the temporal relationship
Alexander M. C. Bowles, C. Williamson, T. Williams, P. Donoghue   +3 more
semanticscholar   +1 more source

Somatic mutations in early metazoan genes disrupt regulatory links between unicellular and multicellular genes in cancer

eLife, 2019
Extensive transcriptional alterations are observed in cancer, many of which activate core biological processes established in unicellular organisms or suppress differentiation pathways formed in metazoans.
Anna S Trigos, Richard B Pearson, Anthony T Papenfuss, David L Goode   +3 more
doaj   +1 more source

Evolutionary connectionism: algorithmic principles underlying the evolution of biological organisation in evo-devo, evo-eco and evolutionary transitions [PDF]

, 2015
The mechanisms of variation, selection and inheritance, on which evolution by natural selection depends, are not fixed over evolutionary time. Current evolutionary biology is increasingly focussed on understanding how the evolution of developmental ...
A Clark, A Crombach, A Davies, A Mesoudi, A Traulsen, A Wagner, A Wagner, Adam Davies, Adam Jackson, AF Bourke, AG Jones, B Gallardo, B Matthews, BE Beisner, C Folke, C. L. Buckley, CA Solari, Chris Cox, CP Doncaster, CR Shalizi, CS Holling, D Schluter, D Simberloff, Daniel Power, DC Queller, DE Rumelhart, DH Ackley, DJ Earl, DM Post, DO Hebb, DS Wilson, DS Wilson, DS Wilson, E Chastain, E Jablonka, E Jablonka, E Jablonka, E Szathmáry, E Szathmáry, EG Leigh, FC Poderoso, FC Santos, FM Bator, G Bateson, G O’Toole, G Ritzer, GB Müller, GC Gallopín, GE Hinton, GE Hinton, GE Hinton, GP Wagner, GP Wagner, GP Wagner, GP Wagner, H Lipson, HE Hoekstra, J Clune, J Draghi, J Gerhart, J Maynard Smith, J Maynard Smith, J Maynard Smith, J Maynard Smith, J Odling-Smee, J Odling-Smee, JD Farmer, JF Fontanari, JH Lawton, JJ Hopfield, JJ Hopfield, JJ Hopfield, JL Hendrikse, JM Montoya, JM Pacheco, JN Thompson, JP Wright, JR Snowdon, K Jax, K Laland, K Sigmund, KN Laland, KN Laland, KN Laland, Kostas Kouvaris, L Margulis, L Margulis, L Margulis, L Partridge, L Valiant, Loizos Kounios, LW Buss, M Blute, M Chicurel, M Gell-Mann, M Hauschild, M Kallich, M Kirchner, M Parter, M Pavlicev, M Pelikan, M Pigliucci, M Pigliucci, M Pigliucci, M Toussaint, M Trestman, MA Nowak, MJ West-Eberhard, ML Johnson, MO Jackson, MO Jackson, N Kashtan, N Kashtan, P Godfrey-Smith, PD Sniegowski, PM Brakefield, R Amundson, R Cropp, R Levins, R Mills, R Riedl, RA Watson, RA Watson, RA Watson, RA Watson, RA Watson, RA Watson, RC Lewontin, RC O’Reilly, RE Michod, RE Michod, RE Michod, RE Michod, Richard A. Watson, Rob Mills, S Huang, S Okasha, S Okasha, S Segbroeck Van, SA Frank, SA Frank, SA Frank, SA Levin, SA Levin, SB Carroll, Simon T. Powers, Simon Tudge, SJ Arnold, ST Powers, T Dayan, T Mitchell, TM Lenton, TM Lenton, TW Schoener, W Ghang, WL Brown, WR Ashby   +156 more
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A nonadaptive explanation for macroevolutionary patterns in the evolution of complex multicellularity

Proceedings of the National Academy of Sciences of the United States of America
“Complex multicellularity,” conventionally defined as large organisms with many specialized cell types, has evolved five times independently in eukaryotes, but never within prokaryotes. A number of hypotheses have been proposed to explain this phenomenon,
Emma P Bingham, W. Ratcliff
semanticscholar   +1 more source

Open problems in synthetic multicellularity

npj Systems Biology and Applications
Multicellularity is one of the major evolutionary transitions, and its rise provided the ingredients for the emergence of a biosphere inhabited by complex organisms.
Ricard V. Solé, Núria Conde-Pueyo, Jordi Pla-Mauri, Jordi Garcia-Ojalvo, Núria Montserrat, M. Levin   +5 more
semanticscholar   +1 more source

Multicellular Features of Phytoplankton

Frontiers in Marine Science, 2018
Microscopic marine phytoplankton drift freely in the ocean, harvesting sunlight through photosynthesis. These unicellular microorganisms account for half of the primary productivity on Earth and play pivotal roles in the biogeochemistry of our planet ...
Adi Abada, Einat Segev
doaj   +1 more source

Group-selection via aggregative propagule-formation enables cooperative multicellularity in an individual based, spatial model.

PLoS Computational Biology
The emergence of multicellularity is one of the major transitions in evolution that happened multiple times independently. During aggregative multicellularity, genetically potentially unrelated lineages cooperate to form transient multicellular groups ...
István Oszoli, István Zachar
doaj   +1 more source