Results 71 to 80 of about 52,301 (321)
Plastic multicellular development of Myxococcus xanthus: genotype–environment interactions in a physical gradient [PDF]
Royal Society Open Science, 2019 In order to investigate the contribution of the physical environment to variation in multicellular development of Myxococcus xanthus, phenotypes developed by different genotypes in a gradient of substrate stiffness conditions were quantitatively ...
Natsuko Rivera-Yoshida +6 more
doaj +1 more source
Cyanobacteria and the Great Oxidation Event:Evidence from genes and fossils [PDF]
, 2015 Cyanobacteria are among the most ancient of evolutionary lineages, oxygenic photosynthesizers that may have originated before 3.0 Ga, as evidenced by free oxygen levels.
Donoghue, Philip +2 more
core +5 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Cell Reports, 2015 Although transcription factors are prevalent among yeast prion proteins, the role of prion-mediated transcriptional regulation remains elusive. Here, we show that the yeast prion [SWI+] abolishes flocculin (FLO) gene expression and results in a complete ...
Zhiqiang Du, Ying Zhang, Liming Li
doaj +1 more source
Metazoans evolved by taking domains from soluble proteins to expand intercellular communication network. [PDF]
, 2015 A central question in animal evolution is how multicellular animals evolved from unicellular ancestors. We hypothesize that membrane proteins must be key players in the development of multicellularity because they are well positioned to form the cell ...
Bowie, James U +3 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Evolution and development: some insights from evolutionary theory
Anais da Academia Brasileira de Ciências, 2001 Developmental biology and evolutionary biology are both mature integrative disciplines which started in the 19th century and then followed parallel and independent scientific pathways.
JEAN R. DAVID
doaj +1 more source
Colony size predicts division of labour in Attine ants [PDF]
, 2014 Division of labour is central to the ecological success of eusocial insects, yet the evolutionary factors driving increases in complexity in division of labour are little known.
Alexander RD +10 more
core +3 more sources
Modulation of bacterial multicellularity via spatio-specific polysaccharide secretion
PLoS Biology, 2020 The development of multicellularity is a key evolutionary transition allowing for differentiation of physiological functions across a cell population that confers survival benefits; among unicellular bacteria, this can lead to complex developmental ...
Salim T. Islam +18 more
semanticscholar +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source