Results 131 to 140 of about 21,386 (303)

Dendritic cells: Key players in human herpesvirus 8 infection and pathogenesis [PDF]

open access: yes, 2014
Human herpesvirus 8 (HHV-8; Kaposi's sarcoma-associated herpesvirus) is an oncogenic gammaherpesvirus that primarily infects cells of the immune and vascular systems.
Akula   +119 more
core   +1 more source

Comparison of the clinical characteristics of TAFRO syndrome and idiopathic multicentric Castleman disease in general internal medicine: a 6‐year retrospective study

open access: yesInternal medicine journal (Print), 2020
Although thrombocytopenia, anasarca, fever, reticulin fibrosis and organomegaly (TAFRO) syndrome was first described as a variant of idiopathic multicentric Castleman disease (CD), patients with TAFRO syndrome demonstrate more aggressive clinical ...
Yoshito Nishimura   +4 more
semanticscholar   +1 more source

IgG4‐Related Disease: Emerging Roles of Novel Genetic Variants, Immune Cell Subsets and Therapeutic Targets

open access: yesAllergy, Volume 80, Issue 10, Page 2738-2754, October 2025.
ABSTRACT IgG4, the least abundant IgG subclass in humans, is increasingly recognised for its involvement in allergic and autoimmune pathologies. Its unique properties, such as the tendency to form half‐molecules (one heavy chain and one light chain) and its generally non‐inflammatory nature, distinguish it from other IgG subclasses.
Louisa Tedesco   +8 more
wiley   +1 more source

Pulmonary Manifestations of Plasma Cell Type Idiopathic Multicentric Castleman Disease: A Clinicopathological Study in Comparison with IgG4-Related Disease

open access: yesJournal of Personalized Medicine, 2020
Plasma cell type idiopathic multicentric Castleman disease (PC-iMCD) occasionally manifests as parenchymal lung disease. This study aimed to elucidate the detailed clinicopathological features of lung lesions in PC-iMCD and compare the findings with ...
M. F. Nishimura   +9 more
semanticscholar   +1 more source

Transformation of HHV‐8‐negative idiopathic multicentric Castleman disease into diffuse large B‐cell lymphoma: A case report from Nepal [PDF]

open access: gold, 2023
Ashwini Gupta   +9 more
openalex   +1 more source

Multicentric Castleman’s Disease: A Challenging Diagnosis

open access: yesPathology & Oncology Research, 2013
Multicentric Castleman's disease (MCD) is a sytemic disorder with flares of non-specific symptoms suggestive of a chronic inflammatory syndrome. It is typically accompanied by generalized lymphadenopathy and multiorgan involvement. Histologically, two main variants of Castleman's disease exist, the hyalin vascular type and the plasma cell variant. Upon
Műzes, Györgyi   +3 more
openaire   +3 more sources

Pruritic Plaque on the Right Lower Limb: A Rare Case of Kimura Disease and Literature Review

open access: yesClinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT Kimura disease, though rare in adolescents, should be considered in cases of persistent itchy nodules. Histopathology confirms diagnosis. Surgical excision is effective for localized lesions, with favorable outcomes. Early recognition prevents misdiagnosis and unnecessary treatments.
Xiaoxiao Liu, Xiaolan Zhang
wiley   +1 more source

Multiple human herpesvirus-8 infection [PDF]

open access: yes, 2003
In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM   +7 more
core   +1 more source

Phase 2 study using oral thalidomide-cyclophosphamide-prednisone for idiopathic multicentric Castleman disease.

open access: yesBlood, 2019
Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disorder. The anti-interleukin 6 (IL-6) therapy siltuximab is not available everywhere, and is not effective for over one-half of patients.
Lu Zhang   +9 more
semanticscholar   +1 more source

A Novel Predictive Model for Idiopathic Multicentric Castleman Disease: The International Castleman Disease Consortium Study.

open access: yesThe Oncologist, 2020
BACKGROUND Patients with multicentric Castleman disease (MCD) who are negative for human immunodeficiency virus and human herpesvirus 8 are considered to have idiopathic MCD (iMCD).
Li Yu   +20 more
semanticscholar   +1 more source

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