Results 11 to 20 of about 21,386 (303)

Candidate biomarkers for idiopathic multicentric Castleman disease

Journal of Clinical and Experimental Hematopathology, 2022
The clinical manifestations of idiopathic multicentric Castleman disease (iMCD) are thought to be caused by an excess of inflammatory cytokines; however, the mechanism is yet to be known. In addition to IL-6, inflammatory cytokines, such as IL-1β and TNF-
R. Sumiyoshi, T. Koga, A. Kawakami
semanticscholar   +3 more sources

International, evidence-based consensus diagnostic criteria for HHV-8-negative/idiopathic multicentric Castleman disease. [PDF]

Blood, 2017
D. Fajgenbaum, T. Uldrick, A. Bagg, D. Frank, David Wu, G. Srkalović, D. Simpson, Amy Y. Liu, D. Menke, S. Chandrakasan, M. Lechowicz, R. Wong, S. Pierson, M. Paessler, J. Rossi, M. Ide, J. Ruth, Michael P. Croglio, Alexander Suarez, V. Krymskaya, A. Chadburn, G. Colleoni, S. Nasta, Raj K. Jayanthan, C. Nabel, C. Casper, A. Dispenzieri, A. Fosså, Dermot Kelleher, R. Kurzrock, P. Voorhees, A. Dogan, K. Yoshizaki, F. van Rhee, É. Oksenhendler, E. Jaffe, K. Elenitoba-Johnson, M. Lim   +37 more
semanticscholar   +2 more sources

Diagnostic and therapeutic challenges in hyaline-vascular idiopathic multicentric Castleman disease: A case report [PDF]

Journal of International Medical Research
The diagnosis of idiopathic multicentric Castleman disease typically requires serum interleukin-6 testing—often inaccessible in resource-limited settings.
Chengbin Lu, Xiaoli Ma, Beibei Liu, Jingyan Wang, Song Luo, Qionghua Luo   +5 more
doaj   +2 more sources

Is TAFRO syndrome a subtype of idiopathic multicentric Castleman disease?

American Journal of Hematology, 2019
Castleman disease (CD) is a rare lymphoproliferative disorder that can be unicentric or multicentric. Multicentric CD (MCD) is further subdivided into human herpesvirus type‐8‐associated, POEMS syndrome‐associated, and idiopathic (iMCD).
Tomoyuki Sakai, Hiroshi Kawabata, Nozomu Kurose   +2 more
exaly   +2 more sources

Idiopathic multicentric Castleman disease

Journal of Cancer Research and Therapeutics, 2023
ABSTRACT An elderly man presented with fever and chills for six months, associated with loss of appetite and weight loss, bilateral edema, and non-tender inguinal lymphadenopathy. The left-sided testicle was bulky, firm, and non-tender.
Vipul Chaudhari, Simran Thakkar, Namita Padwal, Niteen D Karnik   +3 more
openalex   +3 more sources

Plasma proteomics identifies a ‘chemokine storm’ in idiopathic multicentric Castleman disease [PDF]

American journal of hematology/oncology, 2018
S. Pierson, Aaron J Stonestrom, D. Shilling, J. Ruth, C. Nabel, Amrit P. Singh, Yue Ren, K. Stone, Hongzhe Li, F. van Rhee, D. Fajgenbaum   +10 more
semanticscholar   +2 more sources

The Evolution and Recent Advances in Diagnostic Criteria for Idiopathic Multicentric Castleman Disease. [PDF]

Am J Hematol
Idiopathic Multicentric Castleman Disease. ABSTRACT Idiopathic multicentric Castleman disease (iMCD) is a rare cytokine‐driven disorder characterized by systemic inflammation, organ dysfunction, and altered lymph node microscopic architecture. Over the past decade, diagnostic criteria have evolved significantly, integrating clinical, histopathological,
Alnoor F, Spies NC, Kumar J, Samghabadi P, Silva O, Luo MX, Chisholm KM, Zhang J, Rangel A, Ng D, Li P, Ohgami RS.   +11 more
europepmc   +2 more sources

Multicentric Castleman Disease of the Supraglottis: A Surgeons’ Dilemma [PDF]

Iranian Journal of Otorhinolaryngology, 2023
Introduction: An abnormal mass in the head and neck involving the supraglottic and cervical region offers a wide range of differential diagnoses. The pathology is either benign or malignant in nature.
Anna Jumaat, Mohd Razif Mohamad Yunus, Doh Yong, Reena Md Zin, Marina Mat Baki   +4 more
doaj   +1 more source

Idiopathic multicentric Castleman’s disease [PDF]

Terapevticheskii arkhiv, 2020
Idiopathic multicentric Castlemans disease is a rare lymphoproliferative disorder that has many similar laboratory, radiological, clinical and pathological manifestations with various conditions, including IgG4-related disease. Increased activity of cytokines, especially interleukin-6, leads to systemic inflammatory symptoms with the development of ...
V. I. Vasilyev, S. G. Palshina, A. I. Pavlovskaya, N. V. Kokosadze, B. D. Chaltsev, L. A. Shornikova   +5 more
openaire   +3 more sources

Continuous therapy in HHV-8 negative Multicentric Castleman Disease and prolonged progression-free survival [PDF]

Journal of Hematology & Oncology
The optimal treatment endpoints and duration of continuous therapy for multicentric Castleman disease (MCD) remain controversial. We retrospectively analyzed data from 123 patients with Human Herpesvirus (HHV)-8 negative MCD.
Yi Liu, Xuejiao Yin, Shengnan Ding, Jiaying Ge, Liya Ma, Min Yang, Xuxia Luo, Chengli Zhong, Sishi Fang, Qiumei Yao, Li Zhu, Wenjuan Yu, Liping Mao, Juying Wei, Xingnong Ye, De Zhou, Hongyan Tong, Haitao Meng, Jie Jin, Liangshun You   +19 more
doaj   +2 more sources