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Idiopathic multicentric Castleman disease (iMCD) is characterized by the benign proliferation of lymphoid cells in multiple regions. However, the co-occurrence of epithelial malignancy and idiopathic multicentric Castleman disease (iMCD) is rarely ...
Ping-Ruey Chou +4 more
doaj +1 more source
Single-cell landscape of idiopathic Multicentric Castleman Disease in identical twins.
Idiopathic Multicentric Castleman Disease (iMCD) is a rare cytokine-driven disorder characterized by systemic inflammation, generalized lymphadenopathy and organ dysfunction.
Jason Yongsheng Chan +20 more
semanticscholar +1 more source
Idiopathic multicentric Castleman disease: A case report
Castleman disease is a rare disease affecting lymph nodes and is considered a non-clonal lymphoproliferative disorder. It has variable clinical presentation and is divided into clinical and histopathological subtypes.
Anna John , Sheima R Das
doaj +1 more source
Immune evasion of the CD1d/NKT cell axis [PDF]
Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity.
Brutkiewicz, Randy R. +2 more
core +1 more source
Idiopathic multicentric Castleman disease (iMCD) is a rare hematologic disorder with heterogeneous presentations ranging from moderate constitutional symptoms to life-threatening multiorgan system involvement. There are vastly different clinical subtypes,
Mateo Sarmiento Bustamante +12 more
semanticscholar +1 more source
Simultaneous lymph node involvement by Castleman disease and Kaposi sarcoma
Both multicentric Castleman disease and Kaposi sarcoma are more frequently observed in HIV infected patients. The coexistence of these Human herpesvirus 8 related lesions, in the same tissue, has been observed, but literature reports are scant.
Luciana Wernersbach Pinto +1 more
doaj +1 more source
Discovery of Innovative Therapies for Rare Immune-Mediated Inflammatory Diseases via Off-Label Prescription of Biologics: The Case of IL-6 Receptor Blockade in Castleman’s Disease [PDF]
Biologics have revolutionized the field of clinical immunology and proven to be both effective and safe in common immune-mediated inflammatory diseases (IMIDs) such as rheumatoid arthritis, inflammatory bowel diseases, and various hematological disorders.
Amira Assaf +4 more
core +1 more source
Multicentric Castleman’s Disease
Castleman’s disease (CD) is a lymphoproliferative disorder, manifesting clinically as uni‐ centric or multicentric disease and pathologically as hyaline vascular, plasma cell or mixed variants. Multicentric Castleman’s disease (MCD) is the most common form of CD encountered at Chris Hani Baragwanath Academic Hospital (CHBAH). From being a rare disease,
Patel, Moosa +6 more
openaire +3 more sources
Idiopathic Multicentric Castleman Disease
Castleman disease [CD] is a lymphoproliferative disease which has characteristic lymph node histopathology. It is classified into two subtypes as unicentric CD and multicentric CD depending on the number of lymph node regions involved. Here we report a case of an elderly malepresenting with bilateral lower limb swelling, generalized lymphadenopathy and
Sawandika Rupasinghe +2 more
openaire +2 more sources
TAFRO syndrome: A case report and review of the literature
TAFRO syndrome is a rare clinicopathologic variant of idiopathic multicentric Castleman disease characterized by Thrombocytopenia, Ascites (anasarca), myeloFibrosis, Renal dysfunction, and Organomegaly.
Tieying Hou +7 more
doaj +1 more source

