Results 21 to 30 of about 100,904 (261)

Review of the Most Important Design Optimization Technique of Composite Wing [PDF]

INCAS Bulletin, 2016
The scope of wing optimization is to design a structure that meets all the airworthiness demands while minimizing its weight. This paper introduces a review for the most important optimization design tools of composite wings with multiple load cases and ...
Bogdan-Alexandru BELEGA, Mihai MIHAILA-ANDRES   +1 more
doaj   +1 more source

Multidisciplinary Design Optimization in Engineering [PDF]

Mathematical Problems in Engineering, 2013
1 Department of Engineering, Indiana University-Purdue University Fort Wayne, 2101 East Coliseum Boulevard, Fort Wayne, IN 46805-149, USA 2Department of Production Engineering, KTH Royal Institute of Technology, Brinellvagen 68, 100 44 Stockholm, Sweden 3 School of Management, Harbin Institute of Technology, Harbin 150001, China 4Mechatronics Group ...
Zhuming Bi, Lihui Wang, Chong Wu, Guilin Yang, Dan Zhang   +4 more
openaire   +1 more source

Evaluation of Three Design approach of a bipropellant propulsion system including multidisciplinary design optimization, Robust and Optimum-Robust [PDF]

فصلنامه علوم و فناوری فضایی, 2019
Considering the importance of the presence of uncertainties in the design of complex engineering systems, in this research multidisciplinary design optimization process for a bipropellant propulsion system in the presence of uncertainties, which in ...
Amirhossain Adami, Hojat Taei, Mansour Hozuri   +2 more
doaj   +1 more source

Multidisciplinary reliability design optimization under time-varying uncertainties

Advances in Mechanical Engineering, 2016
Degradation failure is one of the main reasons for complex mechanical systems losing their functions. Research on multidisciplinary design optimization under uncertainties should shift from static uncertainties to time-varying uncertainties.
Huanwei Xu, Wei Li, Xin Wang, Cong Hu, Suichuan Zhang   +4 more
doaj   +1 more source

ADMET property prediction via multi-task graph learning under adaptive auxiliary task selection

iScience, 2023
Summary: It is a critical step in lead optimization to evaluate the absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties of drug-like compounds.
Bing-Xue Du, Yi Xu, Siu-Ming Yiu, Hui Yu, Jian-Yu Shi   +4 more
doaj   +1 more source

Aerodynamic design of high-lift devices for enhanced low-height takeoff in wing-in-ground effect craft

Applied Ocean Research
Wing-in-ground effect (WIG) craft represents a class of high-performance ship, utilizing ground effect to achieve ultra-low-height flight with an exceptional lift-to-drag ratio.
Yiheng Wang, Wenping Song, Fuyang Ding, Chengpeng Liu, Zhonghua Han, Yajun Shi   +5 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Analytical Sensitivity Analysis of Dynamic Problems with Direct Differentiation of Generalized-α Time Integration

Machines
In this paper, the direct differentiation of generalized-α time integration is derived, equations are introduced and results are shown. Although generalized-α time integration has found usage, the derivation and the resulting equations for the analytical
Erich Wehrle, Veit Gufler
doaj   +1 more source

A fluid–structure analysis approach and its application in the uncertainty-based multidisciplinary design and optimization for blades

Advances in Mechanical Engineering, 2018
In practical engineering, the choice of blade shape is crucial in the design process of turbine. It is because not only the structural stability but also the aerodynamic performance of turbine depends on the shape of blades.
Debiao Meng, Miao Liu, Shunqi Yang, Hua Zhang, Ran Ding   +4 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source