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Multidisciplinary Design Optimization in Engineering [PDF]

open access: yesMathematical Problems in Engineering, 2013
1 Department of Engineering, Indiana University-Purdue University Fort Wayne, 2101 East Coliseum Boulevard, Fort Wayne, IN 46805-149, USA 2Department of Production Engineering, KTH Royal Institute of Technology, Brinellvagen 68, 100 44 Stockholm, Sweden 3 School of Management, Harbin Institute of Technology, Harbin 150001, China 4Mechatronics Group ...
Zhuming Bi   +4 more
openaire   +1 more source

Multidisciplinary reliability design optimization under time-varying uncertainties

open access: yesAdvances in Mechanical Engineering, 2016
Degradation failure is one of the main reasons for complex mechanical systems losing their functions. Research on multidisciplinary design optimization under uncertainties should shift from static uncertainties to time-varying uncertainties.
Huanwei Xu   +4 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari   +5 more
wiley   +1 more source

Collaborative Multidisciplinary Design Optimization with Neural Networks

open access: yesCoRR, 2021
Proceedings of Machine Learning for Engineering Modeling, Simulation, and Design Workshop at Neural Information Processing Systems ...
Jean de Becdelièvre, Ilan Kroo
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Aerodynamic design of high-lift devices for enhanced low-height takeoff in wing-in-ground effect craft

open access: yesApplied Ocean Research
Wing-in-ground effect (WIG) craft represents a class of high-performance ship, utilizing ground effect to achieve ultra-low-height flight with an exceptional lift-to-drag ratio.
Yiheng Wang   +5 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Analytical Sensitivity Analysis of Dynamic Problems with Direct Differentiation of Generalized-α Time Integration

open access: yesMachines
In this paper, the direct differentiation of generalized-α time integration is derived, equations are introduced and results are shown. Although generalized-α time integration has found usage, the derivation and the resulting equations for the analytical
Erich Wehrle, Veit Gufler
doaj   +1 more source

A fluid–structure analysis approach and its application in the uncertainty-based multidisciplinary design and optimization for blades

open access: yesAdvances in Mechanical Engineering, 2018
In practical engineering, the choice of blade shape is crucial in the design process of turbine. It is because not only the structural stability but also the aerodynamic performance of turbine depends on the shape of blades.
Debiao Meng   +4 more
doaj   +1 more source

Multidisciplinary Design Optimization for Space Applications [PDF]

open access: yes, 2012
Multidisciplinary Design Optimization (MDO) has been increasingly studied in aerospace engineering with the main purpose of reducing monetary and schedule costs.
Riccardi, Annalisa
core  

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