Results 101 to 110 of about 64,573 (264)

Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery

open access: yesAdvanced Science, EarlyView.
Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra   +6 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Magneto‐X Effects in Magnetic Soft Materials and Their Applications

open access: yesAdvanced Science, EarlyView.
This review systematically explores magnetic soft materials (MSMs), a novel class of composites that transform under magnetic fields. It catalogs fundamental “Magneto‐X” effects, classifies materials by their matrix and magnetic fillers, and highlights transformative applications in soft robotics, biomedical devices, flexible electronics, etc. Finally,
Ziyin Xiang   +5 more
wiley   +1 more source

Recent Advances in Sustainable Single‐Atom Catalysts from Biomass and Solid Waste: Design, Synthesis and Applications

open access: yesAdvanced Science, EarlyView.
Biomass‐ and solid waste‐derived sustainable single‐atom catalysts (Sus‐SACs) provide a cost‐effective and renewable approach to catalyst design. This review summarizes precursor selection, including AI‐assisted screening, synthesis strategies with emphasis on ultrafast methods, and advanced characterization techniques.
Hongzhe He   +8 more
wiley   +1 more source

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

open access: yesAdvanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen   +9 more
wiley   +1 more source

Multidisciplinary Optimization of Oral Chemotherapy Delivery at the University of Wisconsin Carbone Cancer Center. [PDF]

open access: yesJ Oncol Pract, 2016
Mulkerin DL   +5 more
europepmc   +1 more source

Tb3+‐Doped Glass‐Ceramic Scintillating Plates and Fibers for X‐Ray Imaging and Flexible Detection

open access: yesAdvanced Science, EarlyView.
A Tb3+‐doped glass‐ceramic scintillator, with controlled Ba2GdF7 nanocrystal precipitation, was developed through a rational design strategy guided by phase diagrams and molecular dynamics simulations. The obtained material exhibits a high light yield of 41 800 photons/MeV (418%/BGO), a spatial resolution of 25.3 lp/mm, and exceptional thermal ...
Songxuan Liu   +6 more
wiley   +1 more source

Vascularized Cardiac Tissue Engineering: From Advances in Biofabrication to Translational Applications

open access: yesAdvanced Science, EarlyView.
This review presents a process‐oriented framework for vascularized cardiac tissue engineering, highlighting how the coordinated design of cells, biomaterials, and biofabrication strategies enables the functional development or vascularized myocardium for disease modelling and drug discovery.
Yang Liu   +9 more
wiley   +1 more source

Terahertz Channel Modeling, Estimation and Localization in RIS‐Assisted Systems

open access: yesAdvanced Electronic Materials, EarlyView.
Reconfigurable intelligent surfaces have become a recent intensive research focus. Based on practical applications, channel strategies for RIS‐assisted terahertz wireless communication systems are categorized into three different types: channel modeling, channel estimation, and channel localization.
Hongjing Wang   +9 more
wiley   +1 more source

Advancing Energy Materials by In Situ Atomic Scale Methods

open access: yesAdvanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
Progress in in situ atomic scale methods leads to an improved understanding of new and advanced energy materials, where a local understanding of complex, inhomogeneous systems or interfaces down to the atomic scale and quantum level is required. Topics from photovoltaics, dissipation losses, phase transitions, and chemical energy conversion are ...
Christian Jooss   +21 more
wiley   +1 more source

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