Results 1 to 10 of about 184,623 (248)

Tazobactam selects for multidrug resistance [PDF]

npj Antimicrobials and Resistance
Piperacillin-Tazobactam is a β-lactam/β-lactamase inhibitor combination that is amongst the most prescribed antimicrobials in hospital medicine.
Emma R. Holden, Muhammad Yasir, A. Keith Turner, Ian G. Charles, Mark A. Webber   +4 more
doaj   +2 more sources

Detection of Class 1 Integron Encoding Gene in Multidrug Resistance (MDR) Citrobacter freundii Isolated from Healthy Broiler Chicken

Tropical Animal Science Journal, 2021
This study was aimed to find out that broiler chicken farms have problems with antibiotic resistance Citrobacter freundii and determined the prevalence and class 1 integron encoding gene.
A. M. Witaningrum, F. J. Wibisono, D. A. Permatasari, M. H. Effendi   +3 more
doaj   +1 more source

The novel potential multidrug-resistance biomarkers for Pseudomonas aeruginosa lung infections using transcriptomics data analysis

Informatics in Medicine Unlocked, 2021
Development of multidrug resistance is the main obstacle for treating infections of Pseudomonas aeruginosa, an opportunistic pathogen responsible for a wide range of persistent infections throughout the body.
Nazanin Hosseinkhan, Abbas Allahverdi, Fereshteh Abdolmaleki   +2 more
doaj   +1 more source

Characterization of a Conjugative Multidrug Resistance IncP-2 Megaplasmid, pPAG5, from a Clinical Pseudomonas aeruginosa Isolate

Microbiology Spectrum, 2022
The spread of resistance genes via horizontal plasmid transfer plays a significant role in the formation of multidrug-resistant (MDR) Pseudomonas aeruginosa strains. Here, we identified a megaplasmid (ca.
Meng Li, Congcong Guan, Gaoyu Song, Xiaoxi Gao, Weina Yang, Tietao Wang, Yani Zhang   +6 more
doaj   +1 more source

Detection of 5 Kinds of Genes Related to Plasmid-Mediated Quinolone Resistance in Four Species of Nonfermenting Bacteria with 2 Drug Resistant Phenotypes

Canadian Journal of Infectious Diseases and Medical Microbiology, 2020
Objective. This study aimed to detect 5 kinds of genes related to plasmid-mediated quinolone resistance in four species of nonfermenting bacteria with 2 drug resistance phenotypes (multidrug resistance and pandrug resistance), which were Acinetobacter ...
De-Song Ming, Qing-Qing Chen, Xiao-Ting Chen   +2 more
doaj   +1 more source

Antimicrobial Resistance Patterns in Clinical Isolates of Enterobacteriaceae from a Tertiary Care Hospital, Kathmandu, Nepal

Nepalese Medical Journal, 2018
Introduction: Multidrug resistance among Enterobacteriaceae is in increasing trend these days. The objective of this study was to determine the antibiogram of clinical isolates of Enterobacteriaceae with special reference to multidrug resistance and ...
Ram Prasad Adhikari, Subha Shrestha, Junu Richhinbung Rai, Ritu Amatya   +3 more
doaj   +1 more source

FRAX486, a PAK inhibitor, overcomes ABCB1-mediated multidrug resistance in breast cancer cells [PDF]

Brazilian Journal of Medical and Biological Research
The overexpression of P-glycoprotein (P-gp/ABCB1) is a leading cause of multidrug resistance (MDR). Hence, it is crucial to discover effective pharmaceuticals that counteract ABCB1-mediated multidrug resistance.
Meng Zhang, Xiaoqi Zeng, Meiling She, Xingduo Dong, Jun Chen, Qingquan Xiong, Guobin Qiu, Shuyi Yang, Xiangqi Li, Guanghui Ren   +9 more
doaj   +1 more source

Multidrug resistance 1 gene polymorphisms may determine Crohn's disease behavior in patients from Rio de Janeiro

Clinics, 2014
OBJECTIVES: Conflicting data from studies on the potential role of multidrug resistance 1 gene polymorphisms in inflammatory bowel disease may result from the analysis of genetically and geographically distinct populations.
Ana Teresa P. Carvalho, Renata S.B. Fróes, Barbara C. Esberard, Juliana C.V.C. Santos, Davy C. M. Rapozo, Ana B. Grinman, Tatiana A. Simão, Pedro Nicolau Neto, Ronir R. Luiz, Antonio José V. Carneiro, Heitor S.P. de Souza, Luis Felipe Ribeiro-Pinto   +11 more
doaj   +1 more source

Analysis of drug resistance in pulmonary tuberculosis patients with positive sputum tuberculosis culture in Northeast China

Frontiers in Pharmacology, 2023
Objective: The objective of this study is to determine the drug resistance status of pulmonary tuberculosis patients in Jilin Province.Methods: A retrospective survey was conducted on 395 sputum culture TB-positive patients admitted to the tuberculosis ...
Li Sichen, Wang Rui, Wang Rui, Yang Yue, Liu Xin, Cui Youbin, Tang Ze, Cai Hongfei   +7 more
doaj   +1 more source

"Emergence of Multidrug Resistant Strains of Escherichia coli Isolated from Urinary Tract Infections" [PDF]

Iranian Journal of Public Health, 2003
The emergence of multidrug resistant strains of Escherichia coli has complicated treatment decision and may lead to treatment failures. From April to November 2001 we prospectively evaluated the prevalence of resistance to trimethoprim-sulfamethoxazole ...
R Moniri, A Khorshidi, H Akbari   +2 more
doaj   +1 more source