Results 1 to 10 of about 150,968 (195)
Expression of multidrug-resistance associated proteins in human retinoblastoma treated by primary enucleation [PDF]
International Journal of Ophthalmology, 2018 AIM: To reveal the expression of multidrug-resistance associated proteins: glutathione-S-transferase π (GSTπ), P-glycoprotein (P-gp) and vault protein lung resistance protein (LRP) in retinoblastoma (RB) without any conservative treatment before primary ...
Li-Juan Tang +6 more
doaj +2 more sources
Characterization of newly isolated lytic bacteriophages active against Acinetobacter baumannii [PDF]
, 2014 Based on genotyping and host range, two newly isolated lytic bacteriophages, myovirus vB_AbaM_Acibel004 and podovirus vB_AbaP_Acibel007, active against Acinetobacter baumannii clinical strains, were selected from a new phage library for further ...
De Vos, Daniel +9 more
core +11 more sources
Expression of multidrug resistance proteins in retinoblastoma [PDF]
International Journal of Ophthalmology, 2017 AIM: To elucidate the mechanism of multidrug resistance in retinoblastoma, and to acquire more insights into in vivo drug resistance. METHODS: Three anticancer drug resistant Y79 human RB cells were generated against vincristine, etoposide or ...
Swati Shukla +8 more
doaj +1 more source
Folium Sennae Increased the Bioavailability of Methotrexate through Modulation on MRP 2 and BCRP
Pharmaceuticals, 2021 Folium Sennae (FS), a popular laxative (Senna), contains polyphenolic anthranoids, whose conjugation metabolites are probable modulators of multidrug resistance-associated proteins (MRPs) and breast cancer resistance protein (BCRP). We suspected that the
Chung-Ping Yu +5 more
doaj +1 more source
Multidrug resistance associated proteins in multidrug resistance [PDF]
Chinese Journal of Cancer, 2012 Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance
Sodani, Kamlesh +3 more
openaire +2 more sources
AIMS Microbiology, 2021 The objective of this study was to elucidate the proteomic mechanisms of drug resistance in HIV-infected African patients. Cell membrane fractions from forty oral Candida isolates isolated from African HIV-positive patients were analysed using HPLC-MS ...
Pedro M D S Abrantes +5 more
doaj +1 more source
Microbiology Spectrum, 2023 Improper use of antibiotics in swine could reduce commensal bacteria and possibly increase pathogen infections via the gut resistome. This study aimed to compare the metaproteomic profiles of the gut resistome and related metabolism in the cecal ...
Pamornya Buthasane +6 more
doaj +1 more source
Colistin Resistance Mechanisms in Human and Veterinary Klebsiella pneumoniae Isolates
Antibiotics, 2022 Colistin (polymyxin E) is increasingly used as a last-resort antibiotic for the treatment of severe infections with multidrug-resistant Gram-negative bacteria.
Manuela Tietgen +5 more
doaj +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2021 Multidrug resistance (MDR) due to enhanced drug efflux activity of tumor cells can severely impact the efficacy of antitumor therapies. We recently showed that increased activity of the efflux transporter P-glycoprotein (P-gp) associated with activation ...
Xieyi Zhang +12 more
doaj +1 more source
Multidrug resistance-associated proteins 3, 4, and 5 [PDF]
Pflügers Archiv - European Journal of Physiology, 2006 We summarize in this paper the recently published results on multidrug resistance-associated proteins 3, 4, and 5 (MRPs 3-5). MRP3 can transport organic compounds conjugated to glutathione, sulfate, or glucuronate, such as estradiol-17beta-glucuronide, bilirubin-glucuronides, and etoposide-glucuronide, and also bile salts and methotrexate.
Piet, Borst +2 more
openaire +2 more sources