Results 91 to 100 of about 150,968 (195)

The Frequency and Clinical Relevance of Multidrug Resistance Protein Expression in Patients with Lymphoma

Turkish Journal of Hematology, 2012
OBJECTIVE: Multidrug resistance is a cause of treatment failure in patients with malignant lymphoma; however, the frequency and clinical relevance of multidrug resistance protein expression are unclear.
Eren Gündüz, Murat Dinçer, Güniz Yıldız, Cengiz Bal, Zafer Gülbaş   +4 more
doaj   +1 more source

Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris [PDF]

, 2017
The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive
Borman, Andrew, Johnson, Elizabeth M., Kean, Ryan, Ramage, Gordon, Rautemaa-Richardson, Riina, Richardson, Malcolm D., Sherry, Leighann   +6 more
core   +4 more sources

The influence of the accessory genome on bacterial pathogen evolution [PDF]

, 2011
Bacterial pathogens exhibit significant variation in their genomic content of virulence factors. This reflects the abundance of strategies pathogens evolved to infect host organisms by suppressing host immunity.
Abu-Ali GS, Adiba S, Alfano JR, Arnold DL, Arnold DL, Arnold DL, Asadulghani M, Baharoglu Z, Baquero F, Barash I, Blondel CJ, Blondel CJ, Brüssow H, Cambray G, Chen J, Chen Y, Choi J, Colinon C, Croucher NJ, Dawes FE, De Gelder L, Diard M, Dillon SC, Douard G, Doyle M, Elsaied H, Fondi M, Freeman VJ, Gartemann KH, Gillings MR, Godfrey SAC, Govind R, Greenberg JT, Grillot-Courvalin C, Groisman EA, Guerin E, Hacker J, Hacker J, Halary S, Hassan F, Hazen TH, Hegstad K, Heinemann JA, Heringa S, Hochhut B, Holden MT, Huang L, Imamovic L, Jackson RW, Jackson RW, Jenner C, Joss M, Jové T, Kearney B, Kers JA, Kiiru JN, Koenig JE, Koenig JE, Krauland MG, Landgraf A, Larsson P, Leplae Rl, León G, Lipps HJ, Lloyd AL, Loftie-Eaton W, Lovell HC, Lovell HC, Manning SD, Marchetti M, Matz C, Maurelli AT, Mazel D, Michael CA, Michael CA, Morris CE, Morris CE, Moura A, Naas T, Nadarasah G, Naka H, Nawaz M, Ogura Y, Paauw A, Partridge SR, Pitman A, Poirel L, Poirel L, Ramirez MS, Rankin DJ, Rezzonico F, Rivas LA, Rodriguez-Martinez JM, Rohmer L, Rosewarne CP, Sajjad A, Salanoubat M, Salzberg SL, Seth-Smith H, Shaheen BW, Siguier P, Siguier P, Smillie C, Smith AB, Song H, Sota M, Steinberg KM, Sundin GW, Sundin GW, Tao L, Treangen TJ, van der Meer JR, van der Veen EL, van Essen-Zandbergen A, Wagner A, Waldor MK, Wiesner M, Woodford N, Yang H, Zhou Z, Zupan J   +120 more
core   +2 more sources

Beyond antimicrobial resistance: MATE-type efflux pump FepA contributes to flagellum formation and virulence in Listeria monocytogenes

Applied and Environmental Microbiology
Listeria monocytogenes is commonly found in nature and can readily contaminate various food products. Efflux pump proteins represent an essential group of proteins in bacteria, playing key roles in numerous biological processes.
Jing Xia, Guo Jiang, Yaru Luo, Zhe Wang, Jingjing Li, Zhanhong Fu, Qian Qin, Jiali Xu, Simin Deng, Mianmian Chen, Yue Han, Lingli Jiang, Houhui Song, Changyong Cheng   +13 more
doaj   +1 more source

Drug resistance in cortical and hippocampal slices from resected tissue of epilepsy patients: no significant impact of P-glycoprotein and Multidrug resistance associated proteins.

Frontiers in Neurology, 2015
Drug resistant patients undergoing epilepsy surgery have a good chance to become sensitive to anticonvulsant medication, suggesting that the resected brain tissue is responsible for drug resistance.
Nora eSandow, Nora eSandow, Simon eKim, Simon eKim, Claudia eRaue, Claudia eRaue, Dennis ePäsler, Dennis ePäsler, Zin-Juan eKlaft, Leandro Leite Antonio, Leandro Leite Antonio, Leandro Leite Antonio, Jan-Oliver eHollnagel, Richard eKovacs, Oliver eKann, Oliver eKann, Peter eHorn, Peter eHorn, Peter eVajkoczy, Martin eHoltkamp, Heinz-Joachim eMeencke, Esper A Cavalheiro, Fritz ePragst, Siegrun eGabriel, Thomas-Nicolas eLehmann, Thomas-Nicolas eLehmann, Uwe eHeinemann   +26 more
doaj   +1 more source

Expressions of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in lung dendritic cells

Life Sciences, 2011
Multidrug resistance protein 1 (MDR1) and multidrug resistance-associated protein 1 (MRP1) are ATP-binding cassette transporters that mediate the efflux of a broad spectrum of substances and xenobiotics from cells in barrier organs. Interestingly, they are expressed in immune cells including some kinds of dendritic cells (DCs).
Hirotsugu, Hasegawa, Naoki, Inui, Takafumi, Suda, Kiyoshi, Shibata, Yutaro, Nakamura, Hiroshi, Watanabe, Hirotoshi, Nakamura, Kingo, Chida   +7 more
openaire   +2 more sources

Development and characterization of a new human hepatic cell line [PDF]

, 2015
The increasing demand and hampered use of primary human hepatocytes for research purposes have urged scientists to search for alternative cell sources, such as immortalized hepatic cell lines.
Berx, Geert, De Craene, Bram, De Kock, Joey, Ramboer, Eva, Rogiers, Vera, Vanhaecke, Tamara, Vinken, Mathieu   +6 more
core   +3 more sources

Y6, an Epigallocatechin Gallate Derivative, Reverses ABCG2-Mediated Mitoxantrone Resistance

Frontiers in Pharmacology, 2019
Multidrug resistance is reported to be related to the transmembrane transportation of chemotherapeutic drugs by adenosine triphosphate-binding cassette (ABC) transporters.
Rui-Qiang Zhao, Rui-Qiang Zhao, Rui-Qiang Zhao, Yan Wen, Yan Wen, Pranav Gupta, Zi-Ning Lei, Chao-Yun Cai, Gang Liang, Dong-Hua Yang, Zhe-Sheng Chen, Yu-An Xie   +11 more
doaj   +1 more source

Effects of a Four-Week High-Dosage Zinc Oxide Supplemented Diet on Commensal Escherichia coli of Weaned Pigs [PDF]

, 2019
Strategies to reduce economic losses associated with post-weaning diarrhea in pig farming include high-level dietary zinc oxide supplementation.
Bethe, Astrid, Eichhorn, Inga, Epping, Lennard, Ghazisaeedi, Fereshteh, Johanns, Vanessa C., Lübke-Becker, Antina, Merle, Roswitha, Pfeifer, Yvonne, Semmler, Torsten, Walther, Birgit, Wieler, Lothar H.   +10 more
core   +2 more sources

Exploiting CRISPR/Cas system in controlling antibiotic resistance of bacteria [PDF]

BioSocial Health Journal
The emergence and spread of antimicrobial resistance is a threat to human health, therefore there is a need to explore new strategies to combat antibiotic-resistant bacteria.
Pourya Gholizadeh, Elnaz Faghfuri, Khudaverdi Ganbarov, Hossein Samadi Kafil   +3 more
doaj   +1 more source