Results 111 to 120 of about 150,968 (195)

Spatial transcriptomics and multi-omics reveal relapse and resistance mechanisms of EndMT-derived CAFs mediated by TNC and FLNC in glioblastoma

Journal of Translational Medicine
Background Chemoresistance and recurrence following treatment are the greatest impediments to the prognosis of glioblastoma (GBM). Increasing evidence indicates that cancer-associated fibroblasts (CAFs) play a significant role in the progression of ...
Li Ji, Die Xia, Yu Zhou, Yaling Hu, Zhenkun Yang, Ying Yin, Jingjing Wang, Bo Zhang, Lingli Gong, Koukou Li, Jian Zou, Mei Wang   +11 more
doaj   +1 more source

Multidrug Resistance-Associated Protein 5 [PDF]

, 2020
openaire   +1 more source

Multidrug Resistance-Associated Protein 4 [PDF]

, 2020
openaire   +1 more source

Efflux excretion of bisdemethoxycurcumin-O-glucuronide in UGT1A1-overexpressing HeLa cells: Identification of breast cancer resistance protein (BCRP) and multidrug resistance-associated proteins 1 (MRP1) as the glucuronide transporters. [PDF]

Biofactors, 2018
Yang J, Zhang B, Qin Z, Li S, Xu J, Yao Z, Zhang X, Gonzalez FJ, Yao X.   +8 more
europepmc   +1 more source

N-acetylcysteine enhances multidrug resistance-associated protein 1

, 2004
Background Resistance of cancer cells against anticancer agents is caused partly by multidrug resistance-associated protein 1 (MRP1). The exact mechanism of MRP1-involved multidrug resistance has not yet been clarified, although glutathione (GSH) is likely to have a role for the resistance to occur. N-acetylcysteine (NAC) is a pro-glutathione drug.
Akan, I, Akan, S, Akca, H, Savas, B, Ozben, T   +4 more
openaire   +2 more sources

Multidrug Resistance-Associated Protein 1 (MRP1) mediated vincristine

, 2005
Background: Multidrug resistance mediated by the multidrug resistance-associated protein 1 (MRP1) decreases cellular drug accumulation. The exact mechanism of MRP1 involved multidrug resistance has not been clarified yet, though glutathione (GSH) is likely to have a role for the resistance to occur. N-acetylcysteine (NAC) is a pro-glutathione drug.
Akan, I, Akan, S, Akca, H, Savas, B, Ozben, T   +4 more
openaire   +2 more sources

Multidrug Resistance-Associated Proteins 3 and 5 Play a Role in the Hepatic Transport of Mercuric Conjugates of Glutathione. [PDF]

Int J Mol Sci
Galiciolli MEA, Joshee L, Oliveira CS, Barkin JL, Bridges CC.   +4 more
europepmc   +1 more source

Therapeutic Opportunities in Infectious Diseases: Highlights from the Society of Medicines Research Symposium, held on March 14th 2013 at the National Heart & Lung Institute, London, UK [PDF]

, 2013
Alderton, W K, Anderson, Rosaleen, Collingwood, S P, Pryde, D C   +3 more
core   +1 more source

Retraction: involvement of DNA methyltransferase 1 (DNMT1) and multidrug resistance-associated proteins in 2-methoxyestradiol-induced cytotoxicity in EC109/Taxol cells. [PDF]

Transl Cancer Res
Yang Q, Guo X, Xu Y, Duan C, Wang H, Feng Q, Zhang N.   +6 more
europepmc   +1 more source

First-in-human evaluation of 6-bromo-7-[¹¹C]methylpurine, a PET tracer for assessing the function of multidrug resistance-associated proteins in different tissues. [PDF]

Eur J Nucl Med Mol Imaging
Mairinger S, Jackwerth M, Chalampalakis Z, Rausch I, Weber M, Wölfl-Duchek M, Pracher L, Nics L, Pahnke J, Langsteger W, Hacker M, Zeitlinger M, Langer O.   +12 more
europepmc   +1 more source