Results 61 to 70 of about 150,968 (195)

Whole-genome survey of the putative ATP-binding cassette transporter family genes in Vitis vinifera. [PDF]

open access: yesPLoS ONE, 2013
The ATP-binding cassette (ABC) protein superfamily constitutes one of the largest protein families known in plants. In this report, we performed a complete inventory of ABC protein genes in Vitis vinifera, the whole genome of which has been sequenced. By
Birsen Çakır, Ozan Kılıçkaya
doaj   +1 more source

Sodium Benzoate is Associated with Salmonella Typhi Resistant to Chloramphenicol [PDF]

open access: yes, 2016
Background: There are many factors that govern growth and resistant of Salmonella typhi. A study had reported that the use of sodium benzoate caused antibiotic resistant.
Anand, J. R. (Jay)   +4 more
core   +1 more source

iTRAQ-Based Differential Proteomic Analysis Reveals the Pathways Associated with Tigecycline Resistance in Acinetobacter baumannii

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Acinetobacter baumannii is an aerobic and Gram-negative bacterial pathogen with high morbidity and mortality. It remains a serious public health problem arising from its multidrug-resistant and extensive antibiotic resistance spectrum ...
Ni Yang   +11 more
doaj   +1 more source

Expression of the multidrug resistance‐associated protein in myelodysplastic syndromes [PDF]

open access: yesBritish Journal of Haematology, 2000
In the myelodysplastic syndromes (MDS), P‐glycoprotein (P‐gp) expression is clinically associated with drug resistance, whereas the clinical significance of multidrug resistance‐associated protein (MRP1) is uncertain. Bone marrow from 56 patients with MDS, including six with refractory anaemia (RA)/RA with ringed sideroblasts (RARS), 23 cases of RA ...
S, Poulain   +7 more
openaire   +2 more sources

Transcriptional responses of Biomphalaria pfeifferi and Schistosoma mansoni following exposure to niclosamide, with evidence for a synergistic effect on snails following exposure to both stressors. [PDF]

open access: yes, 2019
BackgroundSchistosomiasis is one of the world's most common NTDs. Successful control operations often target snail vectors with the molluscicide niclosamide.
Bu, Lijing   +5 more
core   +2 more sources

A cell-based high-throughput screen identifies inhibitors that overcome P-glycoprotein (Pgp)-mediated multidrug resistance.

open access: yesPLoS ONE, 2020
Multidrug resistance (MDR) to chemotherapeutic drugs remains one of the major impediments to the treatment of cancer. Discovery and development of drugs that can prevent and reverse the acquisition of multidrug resistance constitute a foremost challenge ...
Rida Zahra   +5 more
doaj   +1 more source

Differential Effect of Simulated Microgravity on the Cellular Uptake of Small Molecules

open access: yesPharmaceutics
The space environment can affect the function of all physiological systems, including the properties of cell membranes. Our goal in this study was to explore the effect of simulated microgravity (SMG) on the cellular uptake of small molecules based on ...
Odelia Tepper-Shimshon   +12 more
doaj   +1 more source

Application of next-generation sequencing to characterize novel mutations in clarithromycin-susceptible Helicobacter pylori strains with A2143G of 23S rRNA gene

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2018
Background Clarithromycin (CLR) resistance has become a predominant factor for treatment failure of Helicobacter pylori eradication. Although the molecular mechanism of CLR resistance has been clearly understood in H.
Jiaoe Chen   +6 more
doaj   +1 more source

Bioinformatic Analysis for the Validation of Novel Biomarkers for Cancer Diagnosis and Drug Sensitivity [PDF]

open access: yes, 2015
Background: The genetic control of tumour progression presents the opportunity for bioinformatics and gene expression data to be used as a basis for tumour grading.
Lockwood, Laura Anne Rebecca
core   +2 more sources

Type IV Coupling Proteins as Potential Targets to Control the Dissemination of Antibiotic Resistance

open access: yesFrontiers in Molecular Biosciences, 2020
The increase of infections caused by multidrug-resistant bacteria, together with the loss of effectiveness of currently available antibiotics, represents one of the most serious threats to public health worldwide. The loss of human lives and the economic
Itxaso Álvarez-Rodríguez   +6 more
doaj   +1 more source

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