Results 1 to 10 of about 345,615 (256)

Identification of an Outbreak Cluster of Extensively Antibiotic-Resistant GC1 Acinetobacter baumannii Isolates in U.S. Military Treatment Facilities

Microbiology Spectrum, 2023
An outbreak involving an extensively antibiotic-resistant Acinetobacter baumannii strain in three military treatment facilities was identified. Fifty-nine isolates recovered from 30 patients over a 4-year period were found among a large collection of ...
Ting L. Luo, Christopher J. Harmer, Francois Lebreton, Jason Stam, Jason W. Bennett, Ruth M. Hall, Patrick T. Mc Gann   +6 more
doaj   +1 more source

A one-year genomic investigation of Escherichia coli epidemiology and nosocomial spread at a large US healthcare network

Genome Medicine, 2022
Background Extra-intestinal pathogenic Escherichia coli (ExPEC) are a leading cause of bloodstream and urinary tract infections worldwide. Over the last two decades, increased rates of antibiotic resistance in E.
Emma G. Mills, Melissa J. Martin, Ting L. Luo, Ana C. Ong, Rosslyn Maybank, Brendan W. Corey, Casey Harless, Lan N. Preston, Joshua A. Rosado-Mendez, Scott B. Preston, Yoon I. Kwak, Michael G. Backlund, Jason W. Bennett, Patrick T. Mc Gann, Francois Lebreton   +14 more
doaj   +1 more source

Detection of OXA-181-producing Pseudomonas aeruginosa in Germany

International Journal of Medical Microbiology, 2022
Objectives: To report the detection of the class D carbapenemase OXA-181 in an MDR clinical Pseudomonas aeruginosa isolate in Germany. Methods: Carbapenemase detection was performed by using several phenotypic tests such as the modified Hodge test, a ...
Jennifer Schauer, Sören G. Gatermann, Jessica Eisfeld, Jörg Hans, Niels Pfennigwerth   +4 more
doaj   +1 more source

In vivo selection of resistant E. coli after ingestion of milk with added drug residues. [PDF]

, 2014
Antimicrobial resistance represents a major global threat to modern medicine. In vitro studies have shown that very low concentrations of drugs, as frequently identified in the environment, and in foods and water for human and animal consumption, can ...
Bicalho, Rodrigo Carvalho, Pereira, Richard Van Vleck, Siler, Julie D, Warnick, Lorin D   +3 more
core   +13 more sources

Mechanisms of IS26-Mediated Amplification of the aphA1 Gene Leading to Tobramycin Resistance in an Acinetobacter baumannii Isolate

Microbiology Spectrum, 2022
Enhanced levels of resistance to antibiotics arising from amplification of an antibiotic resistance gene that impact therapeutic options are increasingly observed. Amplification can also disclose novel phenotypes leading to treatment failure.
Christopher J. Harmer, Francois Lebreton, Jason Stam, Patrick T. McGann, Ruth M. Hall   +4 more
doaj   +1 more source

An Assessment of Siderophore Production, Mucoviscosity, and Mouse Infection Models for Defining the Virulence Spectrum of Hypervirulent Klebsiella pneumoniae

mSphere, 2021
The pathogenic potential of hvKp strains is primarily mediated by a large virulence plasmid. The minimal set of genes required for the full expression of the hypervirulent phenotype is undefined.
Thomas A. Russo, Ulrike MacDonald, Sidra Hassan, Ellie Camanzo, Francois LeBreton, Brendan Corey, Patrick McGann   +6 more
doaj   +1 more source

Successful Treatment of Acute Prostatitis Caused by Multidrug-Resistant Escherichia coli With Tigecycline Monotherapy [PDF]

, 2020
We present a successful treatment, with tigecycline monotherapy, of acute prostatitis caused by multidrug-resistant Escherichia coli harboring an NDM-1 carbapemenase along with a CMY-2 cephalosporinase and a TEM ...
Babouee Flury, Baharak, Buetti, Niccolo, Casanova, Carlo, Furrer, Hansjakob, Jent, Philipp, Livermore, David M, Lo Priore, Elia, Pelzer, Niklas   +7 more
core   +2 more sources

Economic evaluation of short treatment for multidrugresistant tuberculosis, Ethiopia and South Africa : the STREAM trial [PDF]

, 2020
OBJECTIVE STREAM was a phase-III non-inferiority randomised controlled trial (RCT) to evaluate a shortened regimen for multi-drug resistant tuberculosis (MDR-TB), and included the first-ever within-trial economic evaluation of such regimens, reported ...
Evans, Denise, Girma Tefera, Mamo, HASH(0x5574f3dd52e8), Langley, Ivor, Madan, Jason, Nunn, Andrew, Phillips, Patrick P. J., Rosu, Laura, Ruseng, I. D., Squire, S. Bertel, Tomeny, Ewan M., van Rensburg, Craig   +11 more
core   +4 more sources

Readmissions with multidrug-resistant infection in patients with prior multidrug resistant infection [PDF]

, 2017
OBJECTIVETo determine incidence of and risk factors for readmissions with multidrug-resistant organism (MDRO) infections among patients with previous MDRO infection.DESIGNRetrospective cohort of patients admitted between January 1, 2006, and October 1 ...
Babcock, Hilary M, Burnham, Jason P, Kollef, Marin H, Kwon, Jennie H, Olsen, Margaret A   +4 more
core   +2 more sources

Pseudomonas Endocarditis with an unstable phenotype: the challenges of isolate characterization and Carbapenem stewardship with a partial review of the literature

Antimicrobial Resistance and Infection Control, 2017
Background Pseudomonas endocarditis is exceedingly rare, especially in patients without predisposing risks. We present such a case that included unexpected switches in antibacterial resistance profiles in two Pseudomonas aeruginosa (PA) strains with the ...
Emil Lesho, Erik Snesrud, Yoon Kwak, Ana Ong, Rosslyn Maybank, Maryrose Laguio-Vila, Ann R. Falsey, Mary Hinkle   +7 more
doaj   +1 more source