Results 201 to 210 of about 345,615 (256)

Uncovering Key Characteristics of Antibacterial Peptides through Machine Learning

Macromolecular Rapid Communications, EarlyView.
Machine‐learning (ML) techniques using random forest classification models revealed key characteristics that predict effective antimicrobial peptides (AMPs) targeting Gram‐negative bacteria, Gram‐positive bacteria, and mycobacteria. The ideal cLogP (<$ < $−6) and net‐charge (≤+4) threshold was the same for all three targets with variations in the ...
Jooyoung Roh, Cyrille Boyer, Priyank V. Kumar   +2 more
wiley   +1 more source

Multidrug-resistant Staphylococcus hominis endophthalmitis after cataract surgery: A case report. [PDF]

IDCases
Droulia A, Gyftaki F, Stavrakas P, Papastavrou V, Sykakis E, Margetis G, Margetis A, Tsiogka A.   +7 more
europepmc   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Fluorescent Carbon Dots-Antibiotic Nanocomposite Drug for the Eradication of Multidrug-Resistant Bacteria. [PDF]

ACS Omega
Kumar VB, Shalom Y, Porat Z, Banin E, Gedanken A.   +4 more
europepmc   +1 more source

Nanjing Consensus II on Washed Microbiota Transplantation: Statements From the CHINAGUT Conference

Microbiota Medicine Research, EarlyView.
ABSTRACT The new method of fecal microbiota transplantation, based on automatic facilities and washing processes, was coined as washed microbiota transplantation (WMT). The first recommendations on WMT were released as Nanjing Consensus report by the fecal microbiota transplantation (FMT)‐standardization Study Group in 2019.
Faming Zhang, Sunny Hei Wong, Gaochen Lu, Zheshun Pi, Ting Zhang, Hon Ho Yu, Nan Bu, Xiong Chen, Bota Cui, Dafa Ding, Hainv Gao, Suyu He, Xingxiang He, Shengjuan Hu, Jia Hu, Yunlian Hu, Xiaomeng Jiang, Jiang Jin, Jingnan Li, Pan Li, Juan Liao, Weiwei Liao, Jiang Liu, Ling Liu, Yaping Liu, Yanyan Liu, Yu Liu, Muhan Lv, Xiangjun Meng, Yongzhan Nie, Qian Ren, Lixuan Sang, Yang Sun, Xiaowen Tang, Liangjing Wang, Wei Wang, Xin Wang, Yanling Wei, Quan Wen, Lihao Wu, Xia Wu, Fang Xiao, Lijing Xiong, Shaoqi Yang, Song Yang, Guoliang Ye, Yue Zeng, Huihong Zhai, Xiaoqian Zhang, Yu Zhang, Kun Zhao, Li Zhou, Li Zhu, Kaichun Wu   +53 more
wiley   +1 more source

EEG Dynamics in Children Before, During and After General Anesthesia

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Age‐specific EEG signatures during anesthesia are described in pediatrics, and perioperative monitoring is increasingly advocated; yet most indices and algorithms derive from adult data and may not generalize to early development. Aims The purpose of this study was to characterize perioperative frontal EEGs in young children younger
Maximilian Markus, Feidias Panagiotou, Claudia Spies, Susanne Koch   +3 more
wiley   +1 more source

Correction to: Infection prevention and control measures for multidrug-resistant organisms: a systematic review and network meta-analysis. [PDF]

Infection
Geng Y, Liu Z, Ma X, Pan T, Chen M, Dang J, Zhang P, Chen C, Zhao Y, Pan D, Liang P.   +10 more
europepmc   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

Phytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek, Mesra Aktas, Hale Saybasili, Kutlu O. Ulgen   +3 more
wiley   +1 more source

Multidrug-resistant organism colonization in critically ill cirrhotic patients: Marker or mediator of mortality? [PDF]

World J Hepatol
Bao SS, Lu Y.
europepmc   +1 more source