Results 111 to 120 of about 6,604,045 (304)

Plasmids in the aphid endosymbiont Buchnera aphidicola with the smallest genomes. A puzzling evolutionary story.

open access: yes, 2006
Buchnera aphidicola, the primary endosymbiont of aphids, has undergone important genomic and biochemical changes as an adaptation to intracellular life.
Gil, Rosario   +4 more
core   +1 more source

Localization of the α‐oxoacid dehydrogenase multienzyme complexes within the mitochondrion [PDF]

open access: yesFEBS Letters, 1990
Bovine kidney mitochondria were separated into matrix and membrane fractions by treatment with digitonin and Lubrol PX. While malate dehydrogenase was found essentially in the matrix fraction, both the pyruvate and the α‐oxoglutarate dehydrogenase multienzyme complexes remained bound to the inner membrane fraction and became solubilized only after ...
Edith Maas, Hans Bisswanger
openaire   +3 more sources

Rapid and Visual Detection of Mycobacterium tuberculosis Complex Based on Multiplex Recombinase Polymerase Amplification

open access: yesiLABMED, EarlyView.
We developed an on‐site detection platform for rapid detection of Mycobacterium tuberculosis complex (MTBC) based on the IS1081 gene. The platform utilizes real‐time multiplex recombinase polymerase amplification (mRPA) to achieve a reaction time of less than 30 min.
Xiaoyan Tan   +5 more
wiley   +1 more source

Structure of the transcription open complex of distinct σI factors

open access: yesNature Communications, 2023
Bacterial σI factors of the σ70-family are widespread in Bacilli and Clostridia and are involved in the heat shock response, iron metabolism, virulence, and carbohydrate sensing.
Jie Li   +7 more
doaj   +1 more source

Human 2-Oxoglutarate Dehydrogenase Complex E1 Component Forms a Thiamin-derived Radical by Aerobic Oxidation of the Enamine Intermediate. [PDF]

open access: yes, 2014
Herein are reported unique properties of the human 2-oxoglutarate dehydrogenase multienzyme complex (OGDHc), a rate-limiting enzyme in the Krebs (citric acid) cycle.
Ambrus, Attila   +5 more
core   +4 more sources

Composition and conservation of the mRNA-degrading machinery in bacteria [PDF]

open access: yes, 2011
RNA synthesis and decay counteract each other and therefore inversely regulate gene expression in pro- and eukaryotic cells by controlling the steady-state level of individual transcripts.
Dharam Singh   +2 more
core   +4 more sources

The Role of Magnesium in Liver Cirrhosis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Magnesium is a vital mineral involved in over 300 enzymatic reactions, crucial for physiological functions. Its deficiency, common in liver cirrhosis patients, correlates with poor outcomes by affecting inflammation, oxidative stress, fibrosis, and immunity. This review explores magnesium's role in cirrhosis and its interaction with disease mechanisms.
Weiye Zeng   +4 more
wiley   +1 more source

Assembly of Xylanases into Designer Cellulosomes Promotes Efficient Hydrolysis of the Xylan Component of a Natural Recalcitrant Cellulosic Substrate

open access: yesmBio, 2011
In nature, the complex composition and structure of the plant cell wall pose a barrier to enzymatic degradation. Nevertheless, some anaerobic bacteria have evolved for this purpose an intriguing, highly efficient multienzyme complex, the cellulosome ...
Sarah Moraïs   +6 more
doaj   +1 more source

Novel octaketide macrolides related to 6-deoxyerythronolide B provide evidence for iterative operation of the erythromycin polyketide synthase [PDF]

open access: yes, 2000
Background: The macrolide antibiotic erythromycin A, like other complex aliphatic polyketides, is synthesised by a bacterial modular polyketide synthase (PKS).
Blackaby, Andrew P   +14 more
core   +1 more source

Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients

open access: yesJournal of Lipid Research, 2007
GM1-gangliosidosis and Morquio B disease are lysosomal storage disorders caused by β-galactosidase deficiency attributable to mutations in the GLB1 gene.
Raül Santamaria   +4 more
doaj  

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