Results 21 to 30 of about 5,192,460 (208)

First evidence for a multienzyme complex of lipid biosynthesis pathway enzymes in Cunninghamella bainieri. [PDF]

Sci Rep, 2018
Malic enzyme (ME) plays a vital role in determining the extent of lipid accumulation in oleaginous fungi being the major provider of NADPH for the activity of fatty acid synthase (FAS).
Shuib S, Ibrahim I, Mackeen MM, Ratledge C, Hamid AA.   +4 more
europepmc   +2 more sources

Engineering the 2-Oxoglutarate Dehydrogenase Complex to Understand Catalysis and Alter Substrate Recognition

Reactions, 2022
The E. coli 2-oxoglutarate dehydrogenase complex (OGDHc) is a multienzyme complex in the tricarboxylic acid cycle, consisting of multiple copies of three components, 2-oxoglutarate dehydrogenase (E1o), dihydrolipoamide succinyltransferase (E2o) and ...
Joydeep Chakraborty, Natalia Nemeria, Yujeong Shim, Xu Zhang, Elena L. Guevara, Hetal Patel, Edgardo T. Farinas, Frank Jordan   +7 more
doaj   +1 more source

The Multienzyme Complex Nature of Dehydroepiandrosterone Sulfate Biosynthesis. [PDF]

Int J Mol Sci
Dehydroepiandrosterone (DHEA), a precursor of steroid sex hormones, is synthesized by steroid 17-alpha-hydroxylase/17,20-lyase (CYP17A1) with the participation of microsomal cytochrome b5 (CYB5A) and cytochrome P450 reductase (CPR), followed by sulfation by two cytosolic sulfotransferases, SULT1E1 and SULT2A1, for storage and transport to tissues in ...
Tumilovich A, Yablokov E, Mezentsev Y, Ershov P, Basina V, Gnedenko O, Kaluzhskiy L, Tsybruk T, Grabovec I, Kisel M, Shabunya P, Soloveva N, Vavilov N, Gilep A, Ivanov A.   +14 more
europepmc   +3 more sources

Preparation of a Pectinase-Enriched Multienzyme under Solid State Fermentation of Sugarcane Bagasse

Fermentation, 2023
Enzyme mediated degradation of lignocellulosic biomass is an important step in waste-biorefineries. Multienzyme preparations can effectively degrade complex materials and, hence, can be applied in biorefineries.
Othman M. Alzahrani, Muhammad Sohail, Samy F. Mahmoud, Amal S. Alswat, Yasser El-Halmouch   +4 more
doaj   +1 more source

Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion

Nature Communications, 2021
The pyruvate dehydrogenase complex (PDHc) is a large multienzyme complex that converts pyruvate into acetyl-coenzyme A and in E. coli the core of the PDHc is formed by 24 copies of dihydrolipoyl transacetylase.
Jana Škerlová, Jens Berndtsson, Hendrik Nolte, Martin Ott, Pål Stenmark   +4 more
doaj   +1 more source

Properties of Lactic Acid Microorganisms: Long-Term Preservation Methods [PDF]

Техника и технология пищевых производств, 2018
Among the relevant studies on lactic acid bacteria there are projects devoted to the multienzyme complexes of starter cultures, new competitive bacterial concentrates and their use in fermented functional milk products.
Kriger O., Noskova S.
doaj   +1 more source

Arrangement and symmetry of the fungal E3BP-containing core of the pyruvate dehydrogenase complex

Nature Communications, 2020
The pyruvate dehydrogenase complex (PDC) is a multienzyme complex connecting glycolysis to mitochondrial oxidation of pyruvate. Cryo-EM analysis of PDC from Neurospora crassa reveals localization of fungi-specific protein X (PX) and confirms that it ...
B. O. Forsberg, S. Aibara, R. J. Howard, N. Mortezaei, E. Lindahl   +4 more
doaj   +1 more source

Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly [PDF]

, 2011
Crucial to glucose homoeostasis in humans, the hPDC (human pyruvate dehydrogenase complex) is a massive molecular machine comprising multiple copies of three distinct enzymes (E1–E3) and an accessory subunit, E3BP (E3-binding protein). Its icosahedral E2/
Swetha Vijayakrishnan, Byron, Olwyn, Lindsay, J., Gilbert, David, Cooper, Alan, Lindsay, J.G., Nutley, Margaret A, Philip Callow, Byron, O., Callow, P, David Gilbert, Kropholler, P., Callow, Philip, Byron, O, McGow, D., Vijayakrishnan, S, David, Gilbert, Vijayakrishnan, Swetha, McGow, Donna P., Nutley, M.A., Gilbert, D, Callow, P., Kropholler, P, Alan Cooper, Nutley, Margaret A., Cooper, A., Donna P. McGow, Lindsay, J Gordon, Nutley, M., Lindsay, J. Gordon, Cooper, A, J. Gordon Lindsay, Vijayakrishnan, S., McGow, DP, Margaret A. Nutley, Olwyn Byron, Kropholler, Peter, Peter Kropholler, Mcgow, Donna P, Lindsay, JG, Nutley, MA, McGow, D.P., Gilbert, D.   +42 more
core   +1 more source

Information Transfer in Multienzyme Complexes [PDF]

European Journal of Biochemistry, 1997
Oxidized phosphoribulokinase is almost inactive in its isolated state but becomes active when associated with glyceraldehyde‐3‐phosphate dehydrogenase. There is therefore an information transfer that takes place between these two enzymes. However, when the complex dissociates, free oxidized phosphoribulokinase is even more active than when it is ...
Sandrine Lebreton, Brigitte Gontero, Luisana Avilan, Jacques Ricard   +3 more
openaire   +1 more source

Impact of beta-galactosidase mutations on the expression of the canine lysosomal multienzyme complex [PDF]

, 2009
beta-galactosidase (GLB1) forms a functional lysosomal multienzyme complex with lysosomal protective protein (PPCA) and neuraminidase 1 (NEU1) which is important for its intracellular processing and activity.
Sewell, A.C., Techangamsuwan, S., Baumgärtner, Wolfgang, Kreutzer, R., Sewell, Adrian C, Kreutzer, Robert, Sewell, Adrian C., Techangamsuwan, Somporn, Kreutzer, M., Leeb, Tosso, Baumgartner, W., Kreutzer, Mihaela   +11 more
core   +1 more source