Results 41 to 50 of about 18,450 (254)

Draft genome sequence data of Paenbacillus curdlanolyticus B-6 possessing a unique xylanolytic-cellulolytic multienzyme system

Data in Brief, 2020
Paenibacillus curdlanolyticus B-6 is a facultative anaerobic bacterium that efficiently produces a lignocellulolytic multienzyme complex. The whole genome of P.
Sirilak Baramee, Ayaka Uke, Chakrit Tachaapaikoon, Rattiya Waeonukul, Patthra Pason, Khanok Ratanakhanokchai, Akihiko Kosugi   +6 more
doaj   +1 more source

Human 2-Oxoglutarate Dehydrogenase Complex E1 Component Forms a Thiamin-derived Radical by Aerobic Oxidation of the Enamine Intermediate. [PDF]

, 2014
Herein are reported unique properties of the human 2-oxoglutarate dehydrogenase multienzyme complex (OGDHc), a rate-limiting enzyme in the Krebs (citric acid) cycle.
Ambrus, Attila, Gerfen, Gary, Nemeria, Natalia S., Patel, Hetalben, Tretter, László, Ádám, Veronika   +5 more
core   +1 more source

Membrane-enclosed multienzyme (MEME) synthesis of 2,7-anhydro-sialic acid derivatives [PDF]

, 2017
Naturally occurring 2,7-anhydro-alpha-N-acetylneuraminic acid (2,7-anhydro-Neu5Ac) is a transglycosylation product of bacterial intramolecular trans-sialidases (IT-sialidases).
Andrew Bell, Angata, Bednarski, Chen, Chokhawala, Chokhawala, Crost, Crost, Dimitrios Latousakis, Etzold, Furuhata, Gerardy-Schahn, Gwenaelle Le Gall, Hai Yu, Ian J. Colquhoun, Juge, Juge, Lee, Lewis, Li, Li, Lifely, Louise E. Tailford, Luo, Luo, Marie Monestier, Martin Rejzek, Nathalie Juge, Ouwerkerk, Robert A. Field, Rohrer, Sandra Tribolo, Savage, Schauer, Schroder, Simone Dedola, Suzuki, Tailford, Tailford, Varki, Xi Chen, Yu   +41 more
core   +2 more sources

Cellulase-Xylanase Synergy in Designer Cellulosomes for Enhanced Degradation of a Complex Cellulosic Substrate

mBio, 2010
Designer cellulosomes are precision-engineered multienzyme complexes in which the molecular architecture and enzyme content are exquisitely controlled.
Sarah Moraïs, Yoav Barak, Jonathan Caspi, Yitzhak Hadar, Raphael Lamed, Yuval Shoham, David B. Wilson, Edward A. Bayer   +7 more
doaj   +1 more source

The production of plant natural products beneficial to humanity by metabolic engineering

Current Plant Biology, 2020
Influencing the production of natural products in planta by metabolic engineering approaches has become an increasingly popular means to address a variety of important agricultural, medicinal, and nutraceutical issues.
Rebecca P. Barone, David K. Knittel, Joey K. Ooka, Lexus N. Porter, Noa T. Smith, Daniel K. Owens   +5 more
doaj   +1 more source

Multienzyme Biosynthesis of Dihydroartemisinic Acid

Molecules, 2017
One-pot multienzyme biosynthesis is an attractive method for producing complex, chiral bioactive compounds. It is advantageous over step-by-step synthesis, as it simplifies the process, reduces costs and often leads to higher yield due to the synergistic
Xixian Chen, Congqiang Zhang, Heng-Phon Too   +2 more
doaj   +1 more source

The Role of the Pyruvate Dehydrogenase Complex in the Development of Ischemic-Reperfusion Syndrome

Кубанский научный медицинский вестник, 2022
Background. One of the key components of energy metabolism is the pyruvate dehydrogenase complex (PDC), the activity of which can be targeted by some cytoprotectors. However, their role remains unclear. It is known that the activation of the PDC in tumor
K. A. Popov, Ya. E. Denisova, I. M. Bykov, I. Yu. Tsymbalyuk, G. A. Ermakova, A. G. Zavgorodnyaya, A. S. Shevchenko   +6 more
doaj   +1 more source

Electrochemical determination of microRNAs based on isothermal strand-displacement polymerase reaction coupled with multienzyme functionalized magnetic micro-carriers [PDF]

, 2016
This study was supported by the National Natural Science Foundation of China (81371901), Doctoral Scientific Fund Project of the Ministry of Education of People's Republic of China (20134433110010), the Critical Point-of-Care Testing (CPOCT) Research ...
Alsmadi, Ameres, Bahn, Bo Li, Bo Situ, Campuzano, Chen, Dong, Dong, Ghawana, Hamidi-Asl, Huang, Lagatie, le Provost, Lei Zheng, Lewis, Li, Lin, Liu, Luo, Manriquez, Pankaj Vadgama, Pers, Preechaworapun, Radi, Radwan, Shi, Shi, Situ, Valoczi, Wang, Wang, Wang, Weifeng Lv, Wen Ma, Wen Wang, Wilson, Xiaomao Yin, Yao, Zhang, Zhu, Zou   +41 more
core   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Biocatalytic Regioselective C‐Formylation of Resorcinol Derivatives

Angewandte Chemie, EarlyView.
An acyltransferase from Chromobacterium sphagni (CsATase) was identified that catalyzes the regioselective formylation of resorcinol substrates. The formylation of substituted resorcinol derivatives yielded mono‐formylated products with up to 99% conversion and up to 74% isolated yield.
Lilla Gal, Suresh Rohan, Anna Żądło‐Dobrowolska, Bianca Hilweg, Judith Müller, Kai Tittmann, Wolfgang Kroutil   +6 more
wiley   +2 more sources