Results 111 to 120 of about 928,687 (218)

A Multienzyme Complex Channels Substrates and Electrons through Acetyl-CoA and Methane Biosynthesis Pathways in \u3ci\u3eMethanosarcina\u3c/i\u3e [PDF]

, 2014
Multienzyme complexes catalyze important metabolic reactions in many organisms, but little is known about the complexes involved in biological methane production (methanogenesis). A crosslinking-mass spectrometry (XL-MS) strategy was employed to identify
Buan, Nicole R., Madayiputhiya, Nandu, Nandakumar, Renu, Lopez, Madeline M., Lieber, Dillon J., Catlett, Jennifer, Metcalf, William W.   +6 more
core  

Posttranslational Modifications of p62/SQSTM1 in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang, Xin Jiang, Runing Qiu, Chandra Sugiarto Wijaya, Miaoqin Chen, Jin Wang, Liyuan Zhu, Hongchuan Jin, Lifeng Feng   +8 more
wiley   +1 more source

Functional characterization of a dockerin-containing expansin-like protein from the anaerobic fungus Neocallimastix californiae

Biotechnology for Biofuels and Bioproducts
Background Anaerobic microbes produce multienzyme complexes known as cellulosomes to enhance the degradation of cellulosic substrates. These complexes localize diverse enzymes onto a protein scaffold, where proteins are anchored by dockerin domains ...
Taru Koitto, Anna Pohto, Elizaveta Sidorova, Thu V. Vuong, Merja Penttilä, Emma R. Master   +5 more
doaj   +1 more source

An Integrated Metabolomics and Bioactivity Approach to Characterize Salvia heldreichiana and Salvia tomentosa Extracts

ChemistryOpen, Volume 15, Issue 10, October 2026.
S. heldreichiana and S. tomentosa can be considered as effective sources of natural bioactive agents for further in vivo pharmacological evaluation and development. The genus Salvia, widely known as sage, represents the largest group within the Lamiaceae family and includes numerous species with traditional uses.
Gokhan Zengin, Nilofar Nilofar, Alina Kalyniukova, Vasil Andruch, Giancarlo Angeles Flores, Paola Angelini, Roberto Venanzoni, Kubra Aslan, Ilhami Gulcin, Evren Yildiztugay   +9 more
wiley   +1 more source

Cellulolytic and hemicellulolytic capacity of Acetivibrio clariflavus

Applied Microbiology and Biotechnology
Lignocellulosic biomass represents the largest available renewable source of carbon. It is a recalcitrant mixture of different polysaccharides and lignin.
Katarína Šuchová, Vladimír Puchart
doaj   +1 more source

Engineering Photothermal Nanoplatforms for Multimodal Theranostics and Biosensing

Rare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT Photothermal platforms bridge materials science and biomedicine, emerging as a transformative frontier in biomedical applications. They offer spatiotemporally precise, noninvasive modalities with cell‐type‐independent efficacy for treating a range of diseases.
Xiao Han, Peng Jin, Haiqing Wang, Hao Xue   +3 more
wiley   +1 more source

New Novel Bone Fusion Using TAT-BMP Hydrogel in Rat Model

Global Spine Journal, 2012
Introduction Despite bone fusion using BMP is promising, its clinical applications are limited due to high cost and unwanted ectopic bony fusion. Furthermore, its processing is complicated and low yield.
T. A. Jahng, S. E. Lee, I. S. Noh, J. I. Yook   +3 more
doaj   +1 more source

PmWRKY‐10 Enhances Pine Wilt Disease Resistance by Promoting Pinosylvin Monomethyl Ether Biosynthesis Through Transcriptional Activation of PmPMT2‐1

Molecular Plant Pathology, Volume 27, Issue 10, October 2026.
We identified a PmWRKY‐10→PmPMT2‐1→PME defence pathway in Pinus massoniana against pine wilt disease. PmWRKY‐10 activates PmPMT2‐1 to promote the accumulation of the nematicidal metabolite PME. This discovery reveals the mechanism of stilbene‐mediated resistance and provides key genetic targets for forest management.
Ziyan Nie, Shan Hu, Bin Liu, Qinghua Liu, Hengfu Yin, Zhichun Zhou, Kai Gao   +6 more
wiley   +1 more source

Data-Driven Evolutionary Design of Multienzyme-like Nanozymes

Multienzyme-like nanozymes are nanomaterials with multiple enzyme-like activities and are the focus of nanozyme research owing to their ability to facilitate cascaded reactions, leverage synergistic effects, and exhibit environmentally responsive ...
Ning Sui (2373151), Zibei Chen (18113751), Yujie Jiang (2991267), Zhiling Zhu (3116931)   +3 more
core   +2 more sources

Next‐Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca

ChemBioChem, Volume 27, Issue 17, 14 September 2026.
Biocatalysis is strengthening AstraZeneca's manufacture of active pharmaceutical ingredients through faster development, robust scale‐up, and lower environmental impact. Case studies illustrate where biocatalysis delivers greatest value, while enabling platforms, teams, and partnerships shape its next phase.
Alba Diaz‐Rodriguez, Martin A. Hayes, Keith R. Mulholland, Fernando Tur, Samantha Staniland   +4 more
wiley   +1 more source