Results 81 to 90 of about 928,687 (218)

Colocalization and Disposition of Cellulosomes in Clostridium clariflavum as Revealed by Correlative Superresolution Imaging

open access: yesmBio, 2018
Cellulosomes are multienzyme complexes produced by anaerobic, cellulolytic bacteria for highly efficient breakdown of plant cell wall polysaccharides.
Lior Artzi   +6 more
doaj   +1 more source

Artificial Cell Catalysts for Biotransformation: Design Principles and Process Integration

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Artificial cell catalysts are emerging as programmable biocatalytic platforms for sustainable molecular conversion. By reconstituting enzymes and functional modules within synthetic compartments, they combine the selectivity of biological catalysis with the design flexibility of synthetic materials.
Iori Kobayashi   +2 more
wiley   +1 more source

multienzyme complex

open access: yes, 2014
Citation: 'multienzyme complex' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M04047 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Reactive oxygen and nitrogen species generation features under conditions of acute hepatotoxicity

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2014
Development of the most of pathological conditions occurs by free radical mechanism which is characterized by increased free radical production at the cellular level, especially reactive oxygen and nitrogen species (ROS/RNS).
I. О. Shmarakov   +2 more
doaj   +1 more source

Scale‐Down Platforms for Process‐Oriented Enzyme Screening Using Microfluidics

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Enzyme screening platforms are typically evaluated based on their throughput and analytical performance rather than their ability to mimic the conditions encountered at large scale. In bioreactors, enzymes experience gradients in substrate concentration, oxygen availability, pH, temperature, and interfacial exposure, caused by imperfect mixing
Maria I. Rodriguez‐Torres   +5 more
wiley   +1 more source

Block Copolymer-Quantum Dot Micelles for Multienzyme Colocalization

open access: yes, 2016
To mimic the structure and functionality of multienzyme complexes, which are widely present in Nature, Pluronic-based micelles were designed to colocalize multiple enzymes.
Yanjie Zhang (360019)   +3 more
core   +1 more source

Infrared Laser Heating Reveals a Reversible Phase Transition of Phosphofructokinase 1 in Mammalian Cells

open access: yesChemistry – A European Journal, EarlyView.
In this study, we present a novel method to investigate the phase behavior of biomolecular condensates in living cells. The method complements FRAP experiments, expanding the existing toolbox for characterization of condensates within living cells. ABSTRACT Metabolic enzymes can operate in concerted networks, so‐called metabolons.
Morten Mosbach   +3 more
wiley   +1 more source

Thiamine Diphosphate‐Dependent Biocatalysis in the 21st Century

open access: yesChemistry – A European Journal, EarlyView.
This account summarizes the major discoveries and recent advances, highlighting the biocatalytic abilities, mechanistic studies, and feature‐based classification that are shaping emerging perspectives on thiamine diphosphate (ThDP)‐dependent catalysis.
Lucrezia Lanza   +2 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

open access: yesiNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao   +3 more
wiley   +1 more source

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