Results 71 to 80 of about 37,029 (205)

Comparison of retinal function and macular structure after 27G pars plana vitrectomy with minimal heads‐up versus standard illumination in patients with idiopathic epiretinal membranes: A pilot randomized study

Acta Ophthalmologica, Volume 103, Issue 7, Page e456-e471, November 2025.
Abstract Purpose To analyse the clinical benefits of using the NGENUITY 3D Visualization System in vitreoretinal surgery with low levels of endoillumination, focusing on functional and structural retinal protection in patients with idiopathic epiretinal membranes (ERM). Design Prospective, randomized, comparative study.
Wojciech Lubiński, Tomasz Charabin, Karolina Podborączyńska‐Jodko, Maciej Mularczyk, Ewelina Lachowicz‐Gosławska   +4 more
wiley   +1 more source

Macular function and morphology in acute retinal pigment epithelitis

Indian Journal of Ophthalmology, 2014
A 20-year-old man applied with vision loss in the left eye. Right eye examination was unremarkable. Best-corrected visual acuity (BCVA) in the left eye was 20/200.
Fatih C Gundogan, Oktay Diner, Ahmet Tas, Abdullah Ilhan, Umit Yolcu   +4 more
doaj   +1 more source

Retinal biomarkers in cognitive impairment and dementia: Structural, functional, and molecular insights

Alzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract Cognitive impairment and dementia, including Alzheimer's disease (AD), pose a global health crisis, necessitating non‐invasive biomarkers for early detection. This review highlights the retina, an accessible extension of the central nervous system (CNS), as a window to cerebral pathology through structural, functional, and molecular ...
Yan Min, Hongyu Zhou, Zixiao Li, Yongjun Wang   +3 more
wiley   +1 more source

Outer Retinal Microstructure in a Case of Acute Idiopathic Blind Spot Enlargement Syndrome

Case Reports in Ophthalmology, 2011
Purpose: To present a patient with acute idiopathic blind spot enlargement syndrome who had abnormal changes in the outer retinal microstructure limited to areas with reduced responses on multifocal electroretinograms as well as to the area involving a ...
Michitaka Sugahara, Kei Shinoda, Soiti Celso Matsumoto, Shingo Satofuka, Gen Hanazono, Yutaka Imamura, Atsushi Mizota   +6 more
doaj   +1 more source

Multifocal Electroretinograms in X-Linked Retinoschisis

Investigative Opthalmology & Visual Science, 2003
To study local retinal cone function in patients with X-linked retinoschisis (XLRS) by multifocal ERGs (mfERGs).mfERGs were recorded from seven eyes of seven patients with XLRS (mean age +/- SD, 22.1 +/- 3.2 years; range, 18 to 25 years). Five eyes had microcystic changes in the macula and two eyes had nonspecific macular degeneration.
Chang-Hua, Piao, Mineo, Kondo, Makoto, Nakamura, Hiroko, Terasaki, Yozo, Miyake   +4 more
openaire   +2 more sources

First‐in‐human phase 1 study of KHK2455 monotherapy and in combination with mogamulizumab in patients with advanced solid tumors

Cancer, Volume 131, Issue 13, 1 July 2025.
Abstract Background Indoleamine 2,3‐dioxygenase 1 (IDO1) is a heme‐containing enzyme that degrades tryptophan (Trp) to kynurenine (Kyn), which suppresses effector T cells and reduces antitumor activity. KHK2455 is a long‐acting selective IDO1 inhibitor that blocks the heme component of the IDO holoenzyme.
Timothy A. Yap, Olivier Rixe, Capucine Baldini, Ursa Brown‐Glaberman, Sergey Efuni, David S. Hong, Christophe Massard, Jameel Muzaffar, Andreea Varga, Emrullah Yilmaz, Yuta Ikawa, Lisa H. Shiue, Yi Liu, Matthew W. Hruska, Henry Zhao, Akihiro Tokunaga, Solmaz Sahebjam   +16 more
wiley   +1 more source

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy [PDF]

, 2006
Background: Progressive multifocal leukoencephalopathy (PML) was reported to have developed in three patients treated with natalizumab. We conducted an evaluation to determine whether PML had developed in any other treated patients.
Major, E.O., Clifford, D.B., Habil, M., Fischer, S., Barkhof, F., Yousry, T.A., Hou, J., Radue, E.-W., Ryschkewitsch, C., Mueller-Lenke, N., Jäger, H.R., Sanchez, E., Curfman, B., Miszkiel, K., Fahle, G.   +14 more
core  

The Success of Cataract Surgery and the Preoperative Measurement of Retinal Function by Electrophysiological Techniques

Journal of Ophthalmology, 2015
Purpose. To study the effect of different electrophysiological methods to evaluate retinal function prior to cataract surgery. Methods. Cataract patients who had no significant other eye disease were chosen.
Jing An, Lei Zhang, Yusheng Wang, Zuoming Zhang   +3 more
doaj   +1 more source

Novel Digital Anomalies, Hippocampal Atrophy, and Mutations Expand the Genotypic and Phenotypic Spectra of CNKSR2 in the Houge Type of X‐Linked Syndromic Intellectual Development Disorder (MRXSHG)

American Journal of Medical Genetics Part A, Volume 197, Issue 5, May 2025.
ABSTRACT The Houge type of X‐linked syndromic intellectual developmental disorder (MRXSHG) encompasses a spectrum of neurodevelopmental disorders characterized by intellectual disability (ID), language/speech delay, attention issues, and epilepsy. These conditions arise from hemizygous or heterozygous deletions, along with point mutations, affecting ...
Mohammad‐Reza Ghasemi, Sahand Tehrani Fateh, Afif Ben‐Mahmoud, Vijay Gupta, Lara G. Stühn, Gaetan Lesca, Nicolas Chatron, Konrad Platzer, Patrick Edery, Hossein Sadeghi, Bertrand Isidor, Benjamin Cogné, Heidi L. Schulz, Ilona Krauspe‐Stübecke, Radhakrishnan Periyasamy, Sheela Nampoothiri, Reza Mirfakhraie, Sahar Alijanpour, Steffen Syrbe, Ulrich Pfeifer, Stephanie Spranger, Kathrin Grundmann‐Hauser, Tobias B. Haack, Maria T. Papadopoulou, Tayrine da Silva Gonçalves, Eleni Panagiotakaki, Alexis Arzimanoglou, Seyed Hassan Tonekaboni, Massimiliano Rossi, G. Christoph Korenke, Yves Lacassie, Mi‐Hyeon Jang, Lawrence C. Layman, Mohammad Miryounesi, Hyung‐Goo Kim   +34 more
wiley   +1 more source

ANALYSIS OF THE MULTIFOCAL ELECTRORETINOGRAM OUTCOMES OF COMPUTER VISION SYNDROME: A PROSPECTIVE OBSERVATIONAL CROSS-SECTIONAL CASE-CONTROL STUDY [PDF]

Egyptian Journal of Clinical Ophthalmology
Purpose: To analysis of the multifocal electroretinogram outcomes of computer vision syndrome (CVS). Methods: In this observational cross-sectional case-control study, 59 students were grouped into CVS-diagnosed (n=36 eyes) and control (n=23 eyes).
Elmaghraby, M., Abdellah, M., Sinjab, A., Iqbal, M.   +3 more
doaj   +1 more source