Results 51 to 60 of about 386,727 (312)
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Hausdorff Measurable Multifunctions
Journal of Mathematical Analysis and Applications, 1998 Several notions of measurability for multifunctions are introduced and their relations are explained. The main results concern multifunctions \(F\) defined on the product of two separable complete metric spaces, \(T\) and \(X\). The space \(T\) is endowed with the \(\sigma\)-algebra of measurable sets of a Borel measure \(\mu\) and \(X\) with the ...
PIANIGIANI, GIULIO, F. DE BALSI
openaire +3 more sources
, 2009 Multifunctional structures offer the potential for large savings in the mass and cost of spacecraft missions. By combining the functions of one or more subsystems with the primary structure, mass is reduced and internal volume freed up for additional ...
Roberts, Samuel Charles
core +1 more source
Multifunctional polymeric micelles for delivery of drugs and siRNA
Frontiers in Pharmacology, 2014 Polymeric micelles, self-assembling nano-constructs of amphiphilic copolymers with a core-shell structure have been used as versatile carriers for delivery of drugs as well as nucleic acids.
Aditi M. Jhaveri, Vladimir P. Torchilin
doaj +1 more source
InfoMat, 2022 Surface strain engineering is a promising strategy to design various electrocatalysts for sustainable energy storage and conversion. However, achieving the multifunctional activity of the catalyst via the adjustment of strain engineering remains a major ...
Yu Qiu +5 more
doaj +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Endothelial Cell Proteins as Biomarkers in Susac Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin +11 more
wiley +1 more source
Development of multifunctional titanium-base alloys [PDF]
, 2008 Nano-structurated and Multifunctional Materials Laboratory of the Universidad Carlos III de Madrid (Spain) develops advanced alloys with improved properties for new technological applications.
Pareja, Ramiro
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Adaptive Foam 3D Printing of Ultralight and Multifunctional Materials
Advanced Engineering Materials, EarlyView.Adaptive foam 3D printing, enabled by expandable microspheres, imparts cellular structures to thermoplastic and thermosetting polymers, manufactured through a variety of processes including fused filament fabrication, direct ink writing, digital light processing, and inkjet printing.
Nariman Rajabifar, Amir Ameli
wiley +1 more source