Results 271 to 280 of about 1,269,464 (343)

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Application and challenges of smart responsive multifunctional nanoplatforms in integrated diagnosis and treatment of bladder cancer and overcoming therapeutic resistance. [PDF]

Front Oncol
Chen L, Hang G, Wen Q, Ren L, Chen B.
europepmc   +1 more source

Multifunctional Nanoparticles for Targeted Theranostics

, 2018
openaire   +2 more sources

Albumin Pre-Coating Enhances Intracellular siRNA Delivery of Multifunctional Amphiphile/siRNA Nanoparticles [Retraction]. [PDF]

Int J Nanomedicine
europepmc   +1 more source

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Synthesis and Biomedical Applications of Multifunctional Nanoparticles

Advanced Materials, 2018
The accumulated knowledge of nanoparticle (NP) synthesis for the last 30 years has enabled the development of functional NPs for biomedical applications. Especially, NPs with multifunctional capabilities are gaining popularity as the demand for versatile
Dokyoon Kim, Kwangsoo Shin, S. Kwon, T. Hyeon   +3 more
semanticscholar   +3 more sources

Multifunctional nanoparticles: Analytical prospects

Analytica Chimica Acta, 2010
Multifunctional nanoparticles are among the most exciting nanomaterials with promising applications in analytical chemistry. These applications include (bio)sensing, (bio)assays, catalysis and separations. Although most of these applications are based on the magnetic, optical and electrochemical properties of multifunctional nanoparticles, other ...
Marta Elena Díaz-García
exaly   +3 more sources

Multifunctional nanoparticles inhibit tumor and tumor-associated macrophages for triple-negative breast cancer therapy.

Journal of Colloid and Interface Science, 2023
HYPOTHESIS Tumor-associated macrophages (TAM) are the mainstay of immunosuppressive cells in the tumor microenvironment, and elimination of M2-type macrophages (M2-TAM) is considered as a potential immunotherapy. However, the interaction of breast cancer
Yan Liu, Dan Zhang, Zongquan Zhang, Xiaoya Liang, Xi Yang, Nianhui Ding, Yu Nie, Chunhong Li   +7 more
semanticscholar   +1 more source

Metal-organic framework-mediated multifunctional nanoparticles for combined chemo-photothermal therapy and enhanced immunotherapy against colorectal cancer.

Acta Biomaterialia, 2022
Because of molecular heterogeneity in tumors, clinical outcomes of tumor treatment are not very satisfactory, and novel strategies are therefore needed to address this challenge.
He Liu, Caina Xu, Meng Meng, Shuang Li, Shu Sheng, Sijia Zhang, W. Ni, Huayu Tian, Quan Wang   +8 more
semanticscholar   +1 more source

GSH-Responsive and Hypoxia-Activated Multifunctional Nanoparticles for Synergetically Enhanced Tumor Therapy.

ACS Biomaterials Science & Engineering, 2022
The integration of reactive oxygen species (ROS)-based chemodynamic therapy (CDT) and photodynamic therapy (PDT) has attracted enormous attention for synergistic antitumor therapies.
Chunyang Liu, Sihan Jia, Li Tu, Peiyan Yang, Yange Wang, Sunkui Ke, Wei Shi, S. Ye   +7 more
semanticscholar   +1 more source