Results 291 to 300 of about 1,269,464 (343)

Multifunctional nanoparticles for the treatment and diagnosis of osteosarcoma

Biomaterials Advances, 2023
Osteosarcoma (OS) is a common primary malignant bone tumor in adolescents. Currently, the commonly used treatment strategies for OS include surgery, chemotherapy and radiotherapy. However, these methods have some problems that cannot be ignored, such as postoperative sequelae and severe side effects.
Ping, Yuan, Yajun, Min, Zheng, Zhao
openaire   +2 more sources

Multifunctional nanoparticles for genetic engineering and bioimaging of natural killer (NK) cell therapeutics.

Biomaterials, 2019
Recently, natural killer (NK)-based immunotherapy has attracted attention as a next-generation cell-based cancer treatment strategy due to its mild side effects and excellent therapeutic efficacy.
Kwang-Soo Kim, Jun‐Hyeok Han, Jung-Hoon Park, Hyung-Keun Kim, Seung Hee Choi, Gyeong Ryeong Kim, Haengseok Song, H. An, D. Han, W. Park, Kyung-Soon Park   +10 more
semanticscholar   +1 more source

Precision Cancer Nanotherapy: Evolving Role of Multifunctional Nanoparticles for Cancer Active Targeting.

Journal of Medicinal Chemistry, 2019
Nanoparticles with multifunctionality are being designed and formulated to overcome various limitations of drugs as well as conventional drug delivery systems.
A. Ahmad, F. Khan, R. Mishra, Rehan Khan
semanticscholar   +1 more source

Multifunctional composite core–shell nanoparticles

Nanoscale, 2011
In this review paper, the state-of-the-art knowledge of the core-shell multifunctional nanoparticles (MNPs), especially with unique physiochemical properties, is presented. The synthesis methods were summarized from the aspects of both the advantages and the demerits.
Suying, Wei, Qiang, Wang, Jiahua, Zhu, Luyi, Sun, Hongfei, Lin, Zhanhu, Guo   +5 more
openaire   +2 more sources

Targeted arsenite-loaded magnetic multifunctional nanoparticles for treatment of hepatocellular carcinoma

Nanotechnology, 2019
Arsenic trioxide (ATO), an FDA-approved drug for acute promyelocytic leukemia, also has great potential for treatment of solid tumors. Drug delivery powered by recent advances in nanotechnology has boosted the efficacy of many drugs, which is ...
Xiaoqin Chi, Renyuan Zhang, T. Zhao, Xuanqing Gong, Ruixue Wei, Z. Yin, Hongyu Lin, Dan Li, H. Shan, Jinhao Gao   +9 more
semanticscholar   +1 more source

Targeted Delivery of Multifunctional Magnetic Nanoparticles

Nanomedicine, 2007
Magnetic nanoparticles and their magnetofluorescent analogues have become important tools for in vivo imaging using magnetic resonance imaging and fluorescent optical methods. A number of monodisperse magnetic nanoparticle preparations have been developed over the last decade for angiogenesis imaging, cancer staging, tracking of immune cells (monocyte ...
Jason R, McCarthy, Kimberly A, Kelly, Eric Y, Sun, Ralph, Weissleder   +3 more
openaire   +2 more sources

Innate Immune Activation with Multifunctional Nanoparticles for Cancer Immunotherapy.

Angewandte Chemie
Immune checkpoint blockade (ICB) has revolutionized the treatment of many cancers by leveraging the immune system to combat malignancies. However, its efficacy is limited by the immunosuppressive tumor microenvironment and other regulatory mechanisms of ...
Wenbin Lin, Xiaomin Jiang
semanticscholar   +1 more source

Ratiometric Antifouling Electrochemical Biosensors Based on Multifunctional Peptides and MXene Loaded with Au Nanoparticles and Methylene Blue.

ACS Applied Materials and Interfaces, 2021
A universal strategy for the construction of ratiometric antifouling electrochemical biosensors was developed based on multifunctional peptides and 2D nanomaterial MXene loaded with gold nanoparticles (AuNPs) and methylene blue (MB). The nanocomposite of
Yan Xu, Xin-yan Wang, Caifeng Ding, Xiliang Luo   +3 more
semanticscholar   +1 more source

"Four-In-One" Multifunctional Dandelion-Like Gold@platinum Nanoparticles-Driven Multimodal Lateral Flow Immunoassay.

Small
The traditional lateral flow immunoassay (LFIA) with a single signal output mode may encounter challenges such as low sensitivity, poor detection range, and susceptibility to external interferences.
Zexiang Wang, Rubing Zou, Jiuhong Yi, Yidan Wang, Hong Hu, Chao Qi, Weihua Lai, Yirong Guo, Yunlei Xianyu   +8 more
semanticscholar   +1 more source

Non-viral gene therapy using multifunctional nanoparticles: Status, challenges, and opportunities

Coordination chemistry reviews, 2018
Gene delivery for molecular-level therapeutics is regarded as a prospective remedial route to cure human diseases by the medical community. The major challenge for delivering genes in vivo is the lack of suitable delivery vehicles possessing high ...
Guimiao Lin, Li Li, Nishtha Panwar, Jie Wang, S. Tjin, Xiaomei Wang, K. Yong   +6 more
semanticscholar   +1 more source