Results 191 to 200 of about 70,091 (229)
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Automatic multigenic family annotation: risks and solutions
Trends in Genetics, 2014A major challenge facing bioinformatics today is the efficient annotation of the exponential flow of genomic data. This has led to an increasing dependence on automatic annotation procedures, despite the relatively high error rates of these programs, particularly for multigenic families.
Nizar, Fawal +3 more
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Adaptive evolution of animal toxin multigene families
Gene, 2000Animal toxins comprise a diverse array of proteins that have a variety of biochemical and pharmacological functions. A large number of animal toxins are encoded by multigene families. From studies of several toxin multigene families at the gene level the picture is emerging that most have been functionally diversified by gene duplication and adaptive ...
D, Kordis, F, Gubensek
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Evolution of the Spiroplasma P58 Multigene Family
Biochemical Genetics, 2007Spiroplasma citri and S. kunkelii are prokaryotic phytopathogens transmitted primarily by leafhopper vectors. S. citri BR3-3X was originally isolated from horseradish plants with brittle root disease (Fletcher et al., 1981). Extensive chromosomal rearrangement was found in one derivative of S.
Jana, Comer +3 more
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Molecular evolution of the HSP70 multigene family
Journal of Molecular Evolution, 1994Eukaryotic genomes encode multiple 70-kDa heat-shock proteins (HSP70s). The Saccharomyces cerevisiae HSP70 family is comprised of eight members. Here we present the nucleotide sequence of the SSA3 and SSB2 genes, completing the nucleotide sequence data for the yeast HSP70 family.
W R, Boorstein +2 more
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Multigene families and the evolution of complexity
Journal of Molecular Evolution, 1991Higher organisms are complex, and their developmental processes are controlled by the sequential expression of genes that often form multigene families. Facts are surveyed on how functional diversity of genes is related to duplication of genes or segments of genes, by emphasizing that diversity is often enhanced by alternate splicing and proteolytic ...
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A multigene family of Heteractis magnificalysins (HMgs)
Toxicon, 2008Sea anemones are passive predators. They use their specialized stinging cells (nematocysts) to immobilize any prey that blunders into them. A cnida fires, everting a tubule which delivers toxins that may stick to a prey. These toxins include neurotoxins, cytotoxins, cardiotoxins and haemolysins.
Wang, Y. +3 more
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The multigenic family of monogalactosyl diacylglycerol synthases
Biochemical Society Transactions, 2000Because the synthesis of monogalactosyldiacylglycerol (MGDG) is unique to plants, identified as an important marker of the plastid envelope, involved in a key step of plastid biogenesis and is the most abundant lipid on earth, MGDG synthase activity was extensively analysed at the biochemical and physiological levels.
Eric Marechal +8 more
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Tubulin Isotypes and the Multigene Tubulin Families
1983Publisher Summary This chapter describes tubulin gene structure, evolution, and expression. Microtubules are long filamentous structures that are found ubiquitously in eukaryotic cells and are intimately associated with many cellular functions. The major structural component of microtubules is tubulin, a dimer of α- and β-chains each of about 55,000 ...
N J, Cowan, L, Dudley
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Choosing among Alternative Trees of Multigene Families
Molecular Phylogenetics and Evolution, 2000Estimation of gene trees is the first step in testing alternative hypotheses about the evolution of multigene families. The standard practice for inferring gene family history is to construct trees that meet some objective criteria based on the fit of the character state changes (nucleotide or amino acid changes) to the gene tree.
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Multigene Family Evolution: Perspectives from Insect Chemoreceptors
Trends in Ecology & Evolution, 2015Understanding the birth and diversification of multigene families is a fundamental evolutionary problem. I argue for the insect chemoreceptor superfamily as an outstanding model. Although these receptors are currently the preserve of neuroscientists, putative homologous genes exist in diverse animal and plant genomes, implying an ancient origin ...
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