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Evolution of the Trappin Multigene Family in the Suidae
Journal of Biochemistry, 1998Trappins are a group of secretory proteins containing a WAP motif with an anchoring domain. Previous studies showed that their genes, especially those of pig, have undergone rapid evolution, which produced trappins with a broad spectrum of actions. To understand the evolution of such a rapidly evolving multigene family, we isolated trappin genes of the
Furutani, Y. +5 more
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Structure and evolution of the apolipoprotein multigene family
Journal of Molecular Biology, 1986We present the complementary DNA and deduced amino acid sequence of rat apolipoprotein A-II (apoA-II), and the results of a detailed statistical analysis of the nucleotide and amino acid sequences of all the apolipoprotein gene sequences published to date: namely, those of human and rat apoA-I, apoA-II and apoE, rat apoA-IV, and human apoC-I, C-II and ...
Marsha N. Moore +3 more
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The HSP70 multigene family of Caenorhabditis elegans
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 19901. The heat shock response of the nematode Caenorhabditis elegans has been characterized. 2. There are at least nine genes in the hsp70 multigene family of C. elegans. 3. Five of the hsp70 genes have been characterized and assigned to one of at least three hsp70 gene subfamilies.
Mark F.P. Heschl, David L. Baillie
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The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family.
Genomics, 1996A physiological role for paraoxonase (PON1) is still uncertain, but it catalyzes the hydrolysis of toxic organophosphates. Evidence that the human genome contains two PON1-like genes, designated PON2 and PON3, is presented here.
S. Primo-Parmo +3 more
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Evolution of the Spiroplasma P58 Multigene Family
Biochemical Genetics, 2007Spiroplasma citri and S. kunkelii are prokaryotic phytopathogens transmitted primarily by leafhopper vectors. S. citri BR3-3X was originally isolated from horseradish plants with brittle root disease (Fletcher et al., 1981). Extensive chromosomal rearrangement was found in one derivative of S.
Robert E. Davis +3 more
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Phylogenetics and Computational Biology of Multigene Families
2007This chapter introduces the study of the major evolutionary forces operating in large gene families. The reconstruction of duplication history and phylogenetic analysis provide an interpretative framework of the evolution of multigene families. We present here two case studies, the first coming from Eukaryotes (chemokine receptors) and the second from ...
P. Liò, M. Brilli, FANI, RENATO
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Murine Hox Genes — A Multigene Family
1988The embryonal development of higher organisms is conducted by a network of many different structural and regulatory gene functions whose complexity is yet poorly understood. Some genetic elements identified as being involved in specifying segment identity of the fruit fly Drosophila melanogaster are the homeotic genes (Ouweneel 1976).
Peter Gruss, M. Fibi, Michael Kessel
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Molecular evolution of the HSP70 multigene family
Journal of Molecular Evolution, 1994Eukaryotic genomes encode multiple 70-kDa heat-shock proteins (HSP70s). The Saccharomyces cerevisiae HSP70 family is comprised of eight members. Here we present the nucleotide sequence of the SSA3 and SSB2 genes, completing the nucleotide sequence data for the yeast HSP70 family.
Elizabeth A. Craig +2 more
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Genetic Differentiation of Multigene Families [PDF]
, 1980 Let us consider a situation where a population was split into two identical ones and the two populations have been isolated thereafter. Let Ne be the effective population size of both new and original populations, i. e. the original population has doubled to give the two daughter populations. I shall here apply the simple model of double diffusion. Let
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Tubulin Isotypes and the Multigene Tubulin Families
1983Publisher Summary This chapter describes tubulin gene structure, evolution, and expression. Microtubules are long filamentous structures that are found ubiquitously in eukaryotic cells and are intimately associated with many cellular functions. The major structural component of microtubules is tubulin, a dimer of α- and β-chains each of about 55,000 ...
L Dudley, N J Cowan
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