Perioperative opioid analgesia—when is enough too much? A review of opioid-induced tolerance and hyperalgesia [PDF]
Lancet, The, 2019 Opioids are a mainstay of acute pain management but can have many adverse effects, contributing to problematic long-term use. Opioid tolerance (increased dose needed for analgesia) and opioid-induced hyperalgesia (paradoxical increase in pain with opioid
Lesley A Colvin, Fiona Bull, Tim G Hales
exaly +4 more sources
Effect of a multimodal analgesia strategy on remifentanil daily consumption in mechanically ventilated adult ICU patients: study protocol for a randomised, placebo-controlled, double-blind, parallel-group clinical trial [PDF]
BMJ OpenIntroduction Intensive care unit (ICU) patients under mechanical ventilation experience mild-to-severe pain. International guidelines emphasise the importance and benefits of multimodal analgesia to minimise opioid consumption and its side effects ...
Thibault Mura +7 more
doaj +2 more sources
Continuous peripheral nerve blocks compared to thoracic epidurals or multimodal analgesia for midline laparotomy: a systematic review and meta-analysis [PDF]
Korean Journal of Anesthesiology, 2021 Background Continuous peripheral nerve blocks (CPNBs) have been investigated to control pain for abdominal surgery via midline laparotomy while avoiding the adverse events of opioid or epidural analgesia.
Jonathan G. Bailey +5 more
doaj +1 more source
Asian Journal of Surgery, 2022 Background: As postoperative pain after laparoscopic cholecystectomy may delay recovery and discharge, a multimodal and pre-emptive analgesic approach is necessary.
Jung-Woo Shim +8 more
doaj +1 more source
Multimodal Analgesia Decreases Postoperative Opioid Consumption in Living Liver Donation
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2021 Objective: To evaluate the effects of multimodal analgesia on postoperative opioid consumption and perioperative pain management in patients undergoing living liver donation.
Matthew I. Hardman, DO +2 more
doaj +1 more source
BMJ Open Quality, 2021 Objective Multimodal analgesia pathways have been shown to reduce opioid use and side effects in surgical patients. A quality improvement initiative was implemented to increase the use of multimodal analgesia in adult patients presenting for general ...
Andrea V Olmos +7 more
doaj +1 more source
Multimodal Analgesia in the Aesthetic Plastic Surgery: Concepts and Strategies
Plastic and Reconstructive Surgery, Global Open, 2022 Background:. Postoperative pain management is crucial for aesthetic plastic surgery procedures. Poorly controlled postoperative pain results in negative physiologic effects and can affect length of stay and patient satisfaction.
Anna R. Schoenbrunner, MD, MAS +2 more
doaj +1 more source
OTA International, 2022 . Objectives: To evaluate the effectiveness of multimodal analgesia in patients with a tibial shaft fracture. Design: Retrospective review. Setting: Large, urban, academic center.
Erica Lenk, BSN +2 more
doaj +1 more source
Patient-controlled intravenous morphine analgesia combined with transcranial direct current stimulation for post-thoracotomy pain: A cost-effectiveness study and a feasibility for its future implementation [PDF]
, 2020 This prospective randomized study aims to evaluate the feasibility and cost-effectiveness of combining transcranial direct current stimulation (tDCS) with patient controlled intravenous morphine analgesia (PCA-IV) as part of multimodal analgesia after ...
Dragojevic-Simic, Viktorija +6 more
core +2 more sources
Applied Sciences, 2023 Since there is no consensus on the optimal perioperative analgesic method, the present article provides a brief and practical synthesis on current multimodal pre–postsurgery analgesia protocols for primary TKA (excluding intraoperative anesthetic ...
Simone Franzoni +4 more
doaj +1 more source