Results 21 to 30 of about 19,201 (230)

Multimodal Anesthesia via Opioid-Free Analgesia and Erector Spinae Plane Block

Case Reports in Anesthesiology, 2020
Multimodal anesthesia, which combines general and epidural anesthesia, is used in surgical cases in which a large or painful incision is anticipated. However, both epidural blocks and opioid-based analgesia have limitations in application.
Juan Carlos Luis-Navarro, Carmen Fornés-Rumbao, Ana Bella DeLaCalle-Gil, Mauricio Forero   +3 more
doaj   +1 more source

Does dexmedetomidine reduce postoperative pain after laparoscopic cholecystectomy with multimodal analgesia? [PDF]

Korean Journal of Anesthesiology, 2012
BackgroundPain after laparoscopy is multifactorial and different treatments have been proposed to provide pain relief. Multimodal analgesia is now recommended to prevent and treat post-laparoscopy pain.
Jung-Kyu Park, Soon Ho Cheong, Kun Moo Lee, Se Hun Lim, Jeong Han Lee, Kwangrae Cho, Myoung-Hun Kim, Hyun-Tae Kim   +7 more
doaj   +1 more source

Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring

Advanced Materials Technologies, EarlyView.
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim, Yu‐Jen Cheng, Tianyi Li, Nathan White, Xu Wang, Kristyn Ringgold, Lauren Neidig, Younghoon Kwon, Jae‐Hyun Chung   +8 more
wiley   +1 more source

Gαi1/3 Is a Novel Regulatory Target for RANKL Signal Transduction and Osteoporosis

Advanced Science, EarlyView.
ABSTRACT Osteoporosis, characterized by progressive bone loss and increased fracture risk, is a growing concern as the population ages. Current treatments, though advanced, remain limited, underscoring the necessity for novel therapeutic targets. Recent studies have shown that the immune system plays a key role in osteoporosis, with osteoclasts driving
Chaowen Bai, Mingchao Zhang, Le Liu, Lide Tao, Chenyang Xu, Hao Chai, Xin Shi, Yin Wang, Xiaopei Zhang, Qiong Chen, Dong Liu, Jinyu Bai, Chang She, Xiaozhong Zhou, Cong Cao, Huajian Shan   +15 more
wiley   +1 more source

Pain after sternotomy – review

Brazilian Journal of Anesthesiology, 2016
Background and objective: Adequate analgesia after sternotomy reduces postoperative adverse events. There are various methods of treating pain after heart surgery, such as infiltration with a local anesthetic, nerve block, opioids, non-steroidal anti ...
Ana Paula Santana Huang, Rioko Kimiko Sakata   +1 more
doaj   +1 more source

Mesoscale Recovery of Microglial and Neuronal Dynamics After Craniotomy Across Wide Cortex in Transgenic Mice

Advanced Science, EarlyView.
This study employs longitudinal fluorescence imaging in transgenic mice to map post‐craniotomy cortical recovery. We identify distinct neuroimmune recovery phases: microglial structural inflammation peaks at ∼10 days, neuronal structural intensity peaks at ∼14 days and correlates with microglial activity, and functional network modularity is most ...
Guihua Xiao, Zhilei Wang, Pengchang Zheng, Jingyu Xie, Yangzhen Wang, Yun Chen, Zilin Wang, Ao Li, Minghuan Wang, Quanbo Ji, Can Gao, Di Yao, Lingbo Li, Jiangbei Cao   +13 more
wiley   +1 more source

Comparative study between effect of preoperative multimodal analgesia and pregabalin as unimodal analgesia in reduction of postoperative opioids consumption and postoperative pain in laparoscopic cholecystectomy

Beni-Suef University Journal of Basic and Applied Sciences
Background Laparoscopic cholecystectomy is a popular abdominal surgery and the most common problem for patients undergoing laparoscopic cholecystectomy is the postoperative pain, and associated side effects due to opioids use for pain management and ...
Yassmin M. Kamal, Engy A. Wahsh, Hisham A. Abdelwahab, Walied A. ElBaz, Hazem A. Hussein, Hoda M. Rabea   +5 more
doaj   +1 more source

Multimodal opioid-sparing pain management for emergent cesarean delivery under general anesthesia: a quality improvement project

BMC Anesthesiology, 2022
Background Opioid-sparing multimodal analgesic approach has been shown to provide effective postoperative pain relief and reduce postoperative opioid consumption and opioid-associated adverse effects.
Kelechi B. Anyaehie, Elaine Duryea, Jenny Wang, Chinedu Echebelem, Devin Macias, Mary Sunna, Olutoyosi Ogunkua, Girish P. Joshi, Irina Gasanova   +8 more
doaj   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Effect of Intraoperative Multimodal Analgesia on the Early Postoperative Quality of Recovery in End-stage Head and Neck Cancer Patients Undergoing Open Gastrostomy: A Prospective Randomized Controlled Study

Xiehe Yixue Zazhi
Objective  To evaluate the effect of intraoperative multimodal analgesia on the early postoperative quality of recovery in end-stage head and neck cancer patients undergoing open gastrostomy surgery.  Methods  This was a prospective, parallel, randomized
HU Chunhua, ZHAO Xiaoyan, WU Lili, CHEN hongya, XU Xin, WANG Guyan   +5 more
doaj   +1 more source