Patient-controlled intravenous morphine analgesia combined with transcranial direct current stimulation for post-thoracotomy pain: A cost-effectiveness study and a feasibility for its future implementation [PDF]
, 2020 This prospective randomized study aims to evaluate the feasibility and cost-effectiveness of combining transcranial direct current stimulation (tDCS) with patient controlled intravenous morphine analgesia (PCA-IV) as part of multimodal analgesia after ...
Dragojevic-Simic, Viktorija +6 more
core +2 more sources
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor healthârelated quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Multimodal Analgesia for Spine Surgery: Comment [PDF]
Anesthesiology, 2020 Adam W. Meier +2 more
openalex +4 more sources
Efficacy of Multimodal Analgesia for Postoperative Pain Management in Head and Neck Cancer Patients
Cancers, 2021 Simple Summary Chronic opioid use is a serious global health problem and surgery is often the point of initial exposure for many chronic opioid users.
Ashley V Hinther +9 more
semanticscholar +1 more source
Metabolically Stable Neurotensin Analogs Exert Potent and Long-Acting Analgesia Without Hypothermia [PDF]
Behavioural Brain Research, 405:113189 (2021), 2021 The endogenous tridecapeptide neurotensin (NT) has emerged as an important inhibitory modulator of pain transmission, exerting its analgesic action through the activation of the G protein-coupled receptors, NTS1 and NTS2. Whereas both NT receptors mediate the analgesic effects of NT, NTS1 activation also produces hypotension and hypothermia, which may ...
arxiv +1 more source
BMC Anesthesiology, 2021 Background The Surgical Pleth Index (SPI) is an objective tool that can reflect nociception-antinociception balance and guide the use of intraoperative analgesics. Multimodal analgesia has been neglected in many previous studies.
Jian-guo Guo +4 more
semanticscholar +1 more source
Multimodal analgesia reduces opioid requirements in trauma patients with rib fractures
Journal of Trauma and Acute Care Surgery, 2021 Supplemental digital content is available in the text. BACKGROUND Rib fractures are common in trauma patients and are associated with significant morbidity and mortality.
Shakira W Burton +8 more
semanticscholar +1 more source
Evaluating the efficacy and safety of simple combination of analgesics with and without low dose opioid for perioperative analgesia, hemodynamic and recovery profile in various surgeries posted under general anaesthesia: a prospective randomised controlled study [PDF]
, 2023 Background: Multimodal analgesia is an emerging technique.It has been consistently demonstrated to minimise opioid consumption, related side effects and vital component of enhanced recovery after surgery pathways.
Aruna Kumari S. +3 more
core +2 more sources
Current Therapeutic Research, 2014 Background: Opioid-based postsurgical analgesia exposes patients undergoing laparoscopic colectomy to elevated risk for gastrointestinal motility problems and other opioid-related adverse events (ORAEs).
Keith A. Candiotti, MD +7 more
doaj +1 more source
Annals of Surgical Oncology, 2021 We sought to determine if lumpectomy patients who received perioperative opioid-sparing multimodal analgesia reported less pain when compared with those who received traditional opioid-based care.
C. Morin +9 more
semanticscholar +1 more source