Results 61 to 70 of about 83,050 (301)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
EXPERIMENTAL METHODS OF EXPLORING MULTIMODAL DISCOURSE: CROSSMODAL ALIGNMENT
Вестник Волгоградского государственного университета: Серия 2. ЯзыкознаниеThe study advances Crossmodal Alignment Framework to explore multimodal discourse in its three formats – semiotic, communicative and perceptive – via multimodal experiment.
Mariya I. Kiose +2 more
doaj +1 more source
Immigrant Student Identities in Literacy Spaces [PDF]
, 2018 The United States has a long history of marginalizing immigrant populations. Anti-immigration laws and ideologies have not only marginalized immigrant populations, but they have shaped the American educational system.
Omogun, Lakeya
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Space and Culture, India, 2020 The paper explores the conceptual vision of BRICS in the contemporary world. The study focuses on language and images that are used within BRICS-related institutional communication. We argue that the research is important because of the increasing impact
Anastasia Atabekova +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Multimodal and cognitive approaches to academic discourse in AI-supported learning
Когниция, коммуникация, дискурсThis article examines how academic discourse is reshaped in higher education through the integration of artificial intelligence (AI) and multimodal design, understood here in the sense of multimodal discourse theory (not multimodal AI models).
Ella Dovhaniuk +2 more
doaj +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Using Visual Journals as a Reflective Worldview Window into Educator Identity
, 2020 This ethnographic case study research and content analysis presents the conclusion of a three-year study involving 37 teacher candidate participants across a three-year study within a two year (2 semester program) Bachelor of Education program at a ...
Belcher, Christina, Loerts, Terry
core
Generation of multi-modal dialogue for a net environment [PDF]
, 2002 In this paper an architecture and special purpose markup language for simulated affective face-to-face communication is presented. In systems based on this architecture, users will be able to watch embodied conversational agents interact with each other ...
Baumann, S. +8 more
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