Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Data Source Importance Evaluation for Highway Networks: A Complex Network-Based Approach
Data collection technologies or data sources are critical for highway network management. However, due to the limitations on available management resources, determining the importance of these data sources is necessary to allocate these resources ...
Huangqin HUANG +3 more
doaj +1 more source
This study proposes utility-based accessibility measures and a weibit-based analysis method for analyzing multi-modal transportation network vulnerability. To account for the multi-dimensional travel choice behavior in multi-modal transportation networks,
Yu Gu +2 more
doaj +1 more source
Desire to change one's multimodality and its relationship to the use of different transport means
Using data collected from French employees of a transportation institute and residents of the US San Francisco Bay Area, we operationalize a segmentation of mobility patterns based on objective, subjective, and desired amounts of mobility by various ...
Diana, Marco, Mokhtarian P.L
core +3 more sources
In this experimental study, the mechanical properties of additively manufactured Ti‐6Al‐4V lattice structures of different geometries are characterized using compression, four point bending and fatigue testing. While TPMS designs show superior fatigue resistance, SplitP and Honeycomb lattice structures combine high stiffness and strength. The resulting
Klaus Burkart +3 more
wiley +1 more source
Cities across the world are expanding as a result of urbanization, resulting in growing demand for goods and services, mainly through online sales. This has resulted in the need for an urban consolidation center (UCC) to minimize travel and optimize ...
Oyegoke Teslim Bukoye, Sathvik Gadiraju
doaj +1 more source
A decision support system to improve service quality in multimodal rapid rail systems: A bayesian perspective [PDF]
Copyright @ 2011 International Conference on Computers and Industrial EngineeringIn this study, the accessibility of the rail transit stations in a multimodal network formed by a trunk line and its feeder lines are defined. Connectivity between lines and
Aktas, E, Topcu, I, Ugurlu, S
core
Book Review: Multimodal transport security: Frameworks and policy applications in freight and passenger transport: Joseph Syzliowicz, Luca Zampari, Genserik Reniers and Dawna Rhoades (editors) Edward Elger Publishing, Chelterhan, Uk and Northampton, MA, USA, ISBN 978 1 78347 481 3 [PDF]
This edited collection is part of the series ‘Comparative Perspectives on Transportation Security’, also edited by Syzliowicz and Zampari. The previous book in this series (2014) focussed on maritime security.
Newton, Andrew D.
core +2 more sources
Quantum Emitters in Hexagonal Boron Nitride: Principles, Engineering and Applications
Quantum emitters in hexagonal boron nitride have emerged as a promising candidate for quantum information science. This review examines the fundamentals of these quantum emitters, including their level structures, defect engineering, and their possible chemical structures.
Thi Ngoc Anh Mai +8 more
wiley +1 more source

