Results 31 to 40 of about 431,827 (296)

Case Report: A rare case of recurrent ascites after anti-Claudin18.2 antibody therapy for metastatic gastric cancer while responding sustainingly

Frontiers in Oncology, 2023
BackgroundGastric cancer remains one of the deadliest malignancies in the world, thus urgently requiring effective and safe therapeutics. Claudin18.2 is a member of the tight junction protein family specifically expressed in gastric cancer cells ...
Jinlu Liu, Dan Jiang, Qingqiang Lei, Qing Zhu, Hong Zhu   +4 more
doaj   +1 more source

Acute Thrombotic Coronary Occlusion in a Patient with Coronary Artery Anomaly

Journal of Interdisciplinary Medicine, 2017
Patients with coronary artery anomalies are more susceptible to develop acute thrombotic coronary occlusions due to the abnormal anatomy of these arteries and the disturbance of the pathophysiological mechanisms that lead to an accelerated ...
Beganu Elena, Himcinschi Elisabeta, Hodas Roxana, Cernica Daniel, Rodean Ioana   +4 more
doaj   +1 more source

Combining immune checkpoint inhibitors with thoracic radiotherapy enhances outcomes in advanced non-small-cell lung cancer: a real-world study

Frontiers in Oncology
BackgroundWe aimed to evaluate the efficacy of thoracic radiotherapy (TRT) combined with immune checkpoint inhibitors (ICIs) in patients with advanced non-small-cell lung cancer (NSCLC) in real-world clinical settings and identify predictive subgroups ...
Yao Zou, Yao Zou, Yao Zou, Yichong Chen, Xiaojuan Zhou, Youling Gong, Yong Xu, Bingwen Zou, Feng Peng, Meijuan Huang, You Lu, Yongmei Liu   +11 more
doaj   +1 more source

Actual Dose-Reduction Strategies in Cardiac Computed Tomography

Journal of Interdisciplinary Medicine, 2017
Computed tomography (CT) in cardiac examination is a powerful imaging tool that has developed rapidly during the last decade and continues to increase its potential by bringing novel technologies.
Cernica Daniel, Hodas Roxana, Himcinschi Elisabeta, Beganu Elena, Benedek Theodora   +4 more
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

SLC31A1 Identifying a Novel Biomarker with Potential Prognostic and Immunotherapeutic Potential in Pan-Cancer

Biomedicines, 2023
Solute carrier family 31 member 1 (SLC31A1) encodes a protein that functions as a homotrimer for the uptake of dietary copper. As a vital member of the cuproptosis gene family, it plays an essential role in both normal tissues and tumors.
Pei Zhang, Heqi Yang, Kaiguo Zhu, Chen Chang, Wanrui Lv, Ruizhen Li, Xiaoying Li, Tinghong Ye, Dan Cao   +8 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Hybrid Imaging in the Assessment of Myocardial Ischemia and Viability

Journal of Interdisciplinary Medicine, 2016
Myocardial ischemia results from a reduction in blood flow as a consequence of a coronary stenosis, which produces ischemia in the myocardial territories irrigated by the stenotic artery.
Stănescu Alexandra, Opincariu Diana, Rat Nora, Morariu Mirabela, Condrea Sebastian, Benedek Imre, Benedek Theodora   +6 more
doaj   +1 more source

Cardiovascular Imaging in Infective Endocarditis: A Multimodality Approach.

Circulation Cardiovascular Imaging, 2020
Multimodality imaging plays a pivotal role in the evaluation and management of infective endocarditis (IE)-a condition with high morbidity and mortality.
S. Horgan, Anuj Mediratta, L. Gillam
semanticscholar   +1 more source

Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay, E. Vichayanrat, F. Bremner, F. Valerio, R. Mackenzie, G. Chiaro, G. Ingle, P. McNamara, L. Watson, J. N. Panicker, M. P. Lunn, C. Mathias, V. Iodice   +12 more
wiley   +1 more source