Results 61 to 70 of about 544,818 (296)

Continuous Evolution System Based on Toxin–Antitoxin System Combined with Base Deaminase Accelerates the In Vivo Modification of Target Proteins

open access: yesAdvanced Science, EarlyView.
The promoted Escherichia coli‐assisted continuous evolution (PEACE) system operates through a stringent three step genetic circuit: target gene mutation via a deaminase–T7 RNA polymerase (T7 RNAP) fusion, coupling variant function to antitoxin expression, and growth based selection of surviving cells.
Xinyu Zhang   +10 more
wiley   +1 more source

Controlling multimode optomechanical interactions via interference

open access: yesPhysical Review A, 2017
We demonstrate optomechanical interference in a multimode system, in which an optical mode couples to two mechanical modes. A phase-dependent excitation-coupling approach is developed, which enables the observation of constructive and destructive optomechanical interferences.
Kuzyk, Mark C., Wang, Hailin
openaire   +3 more sources

Nanoparticle‐Mediated TIPE1 mRNA Delivery Enhances Paclitaxel Sensitivity in Triple‐Negative Breast Cancer by Modulating RAB7A Ubiquitination‐Associated Stability and Autophagy

open access: yesAdvanced Science, EarlyView.
TIPE1m NPs nanoparticles restore TIPE1 expression, promote RAB7A ubiquitination and degradation, suppress autophagic flux, and resensitize paclitaxel‐resistant triple‐negative breast cancer to therapy. ABSTRACT Acquired paclitaxel (PTX) resistance remains a major obstacle in triple‐negative breast cancer (TNBC) treatment.
Wei Hu   +9 more
wiley   +1 more source

Engineering Large‐Grain Metal Halide Perovskite Films via Chemical Vapor Deposition for High‐Performance, Ultralow‐Noise Perovskite Photodetectors

open access: yesAdvanced Science, EarlyView.
Chemical vapor deposition produces large‐grain, phase‐pure CsPbBr3 films (grains up to 35 µm) with Drude‐like terahertz photoconductivity and twofold higher carrier mobility versus spin‐coated references. These microstructural advances translate into photodetectors with a detectivity of 8.4 × 1012 Jones, dark current below 1 pA cm−2, X‐ray sensitivity ...
Roel Vanden Brande   +14 more
wiley   +1 more source

Design of a 1 × 3 Power Splitter Based on Multimode Interference in a Parabolic-Type Slot-Waveguide Structure

open access: yesApplied Sciences
Multimode interference (MMI) couplers based on silicon slot-waveguide structures have received widespread attention in recent years. The key issues that need to be addressed are the size and loss of such devices.
Shuo Liu   +8 more
doaj   +1 more source

Multimode nonlinear fibre optics: theory and applications [PDF]

open access: yes, 2012
Optical fibres have been developed as an ideal medium for the delivery of optical pulses ever since their inception (Kao & Hockham, 1966). Much of that development has been focused on the transmission of low-energy pulses for communication purposes ...
Horak, Peter   +3 more
core   +2 more sources

All-fiber multimode interference micro-displacement sensor [PDF]

open access: yes, 2013
We report an all-fiber micro-displacement sensor based on multimode interference (MMI) effects. The micro-displacement sensor consists of a segment of No-Core multimode fiber (MMF) with one end spliced to a segment of single mode fiber (SMF) which acts ...
José Javier Sánchez Mondragón
core  

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

open access: yesAdvanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang   +18 more
wiley   +1 more source

Optical Fiber Head Sensors with Controlled Polarization for Flow Measurement in Pipelines [PDF]

open access: yesJournal of Microwaves, Optoelectronics and Electromagnetic Applications
This experimental study discusses developing methodologies linked to optical fiber sensing (OFS), focused on structural health monitoring with sensors based on multimodal interference and the core diameter mismatch approach to monitor the flow of single ...
Ivenso da S. V. Sualehe   +4 more
doaj   +2 more sources

Two-colour interferometry and switching through optomechanical dark mode excitation

open access: yesNature Communications, 2020
Efficient switching and routing of photons of different wavelengths is desirable for future quantum information applications. To this end the authors demonstrate interference in a multimode system between two optomechanically induced transparency ...
David P. Lake   +3 more
doaj   +1 more source

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